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Identification of a Minimal Cis-Element and Cognate Trans-factor(s) Required for Induction of Rac2 Gene Expression During K562 Cell Differentiation

Rac2 is a Rho family GTPase that is widely expressed in hematopoietic cells and plays a critical role in host defense. This study investigates the mechanisms responsible for increased Rac2 gene expression during myeloid cell differentiation. Treatment of K562 chronic myelogenous leukemia cells with...

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Main Authors: Muthukrishnan, Rajarajeswari, Skalnik, David G.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2697498/
https://ncbi.nlm.nih.gov/pubmed/19376210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2009.04.005
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