CpG Binding Protein Is Crucial for Early Embryonic Development

Epigenetic modification of DNA via CpG methylation is essential for the proper regulation of gene expression during embryonic development. Methylation of CpG motifs results in gene repression, while CpG island-containing genes are maintained in an unmethylated state and are transcriptionally active....

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Detalhes bibliográficos
Main Authors: Carlone, Diana L., Skalnik, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC99931/
https://ncbi.nlm.nih.gov/pubmed/11604496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.22.7601-7606.2001
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