Polyarticular arthritis as presenting feature of farber disease: a lysosomal storage disease involving inflammation

Por Sólyom, Alexander, Karabul, Nesrin, Hügle, Boris, Simonaro, Calogera, Schuchman, Edward
Publicado em 2014

Involvement of the Toll-like receptor 4 pathway and use of TNF-α antagonists for treatment of the mucopolysaccharidoses

Por Simonaro, Calogera M., Ge, Yi, Eliyahu, Efrat, He, Xingxuan, Jepsen, Karl J., Schuchman, Edward H.
Publicado em 2009

Anti-TNF-Alpha Therapy Enhances the Effects of Enzyme Replacement Therapy in Rats with Mucopolysaccharidosis Type VI

Por Eliyahu, Efrat, Wolfson, Theodore, Ge, Yi, Jepsen, Karl J., Schuchman, Edward H., Simonaro, Calogera M.
Publicado em 2011

The Demographics and Distribution of Type B Niemann-Pick Disease: Novel Mutations Lead to New Genotype/Phenotype Correlations

Por Simonaro, Calogera M., Desnick, Robert J., McGovern, Margaret M., Wasserstein, Melissa P., Schuchman, Edward H.
Publicado em 2002

Identification and Characterization of Eight Novel SMPD1 Mutations Causing Types A and B Niemann-Pick Disease

Por Desnick, Jonathan P, Kim, Jungmin, He, Xingxuan, Wasserstein, Melissa P, Simonaro, Calogera M, Schuchman, Edward H
Publicado em 2010

Structural, Compositional, and Biomechanical Alterations of the Lumbar Spine in Rats with Mucopolysaccharidosis Type VI (Maroteaux–Lamy Syndrome)

Por Lai, Alon, Simonaro, Calogera M., Schuchman, Edward H., Ge, Yi, Laudier, Damien M., Iatridis, James C.
Publicado em 2012

Imprinting at the SMPD1 Locus: Implications for Acid Sphingomyelinase–Deficient Niemann-Pick Disease

Por Simonaro, Calogera M., Park, Jae-Ho, Eliyahu, Efrat, Shtraizent, Nataly, McGovern, Margaret M., Schuchman, Edward H.
Publicado em 2006

Mechanism of Glycosaminoglycan-Mediated Bone and Joint Disease : Implications for the Mucopolysaccharidoses and Other Connective Tissue Diseases

Por Simonaro, Calogera M., D’Angelo, Marina, He, Xingxuan, Eliyahu, Efrat, Shtraizent, Nataly, Haskins, Mark E., Schuchman, Edward H.
Publicado em 2008

Dose Responsive Effects of Subcutaneous Pentosan Polysulfate Injection in Mucopolysaccharidosis Type VI Rats and Comparison to Oral Treatment

Por Frohbergh, Michael, Ge, Yi, Meng, Fanli, Karabul, Nesrin, Solyom, Alexander, Lai, Alon, Iatridis, James, Schuchman, Edward H., Simonaro, Calogera M.
Publicado em 2014

Acid Ceramidase Treatment Enhances the Outcome of Autologous Chondrocyte Implantation in a Rat Osteochondral Defect Model

Por Frohbergh, Michael E., Guevara, Johana M., Grelsamer, Ronald P., Barbe, Mary F., He, Xingxuan, Simonaro, Calogera M., Schuchman, Edward H.
Publicado no Osteoarthritis Cartilage (2015)

Enzyme replacement therapy for Farber disease: Proof-of-concept studies in cells and mice

Por He, Xingxuan, Dworski, Shaalee, Zhu, Changzhi, DeAngelis, Victor, Solyom, Alex, Medin, Jeffrey A., Simonaro, Calogera M., Schuchman, Edward H.
Publicado no BBA Clin (2017)

Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses

Por Schuchman, Edward H., Ge, Yi, Lai, Alon, Borisov, Yury, Faillace, Meghan, Eliyahu, Efrat, He, Xingxuan, Iatridis, James, Vlassara, Helen, Striker, Gary, Simonaro, Calogera M.
Publicado em 2013

Oral glycotoxins are a modifiable cause of dementia and the metabolic syndrome in mice and humans

Por Cai, Weijing, Uribarri, Jaime, Zhu, Li, Chen, Xue, Swamy, Shobha, Zhao, Zhengshan, Grosjean, Fabrizio, Simonaro, Calogera, Kuchel, George A., Schnaider-Beeri, Michal, Woodward, Mark, Striker, Gary E., Vlassara, Helen
Publicado em 2014

Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs

Por Simonaro, Calogera M., Tomatsu, Shunji, Sikora, Tracy, Kubaski, Francyne, Frohbergh, Michael, Guevara, Johana M., Wang, Raymond Y., Vera, Moin, Kang, Jennifer L., Smith, Lachlan J., Schuchman, Edward H., Haskins, Mark E.
Publicado no PLoS One (2016)

Acid Ceramidase Maintains the Chondrogenic Phenotype of Expanded Primary Chondrocytes and Improves the Chondrogenic Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells

Por Simonaro, Calogera M., Sachot, Sylvain, Ge, Yi, He, Xingxuan, DeAngelis, Victor A., Eliyahu, Efrat, Leong, Daniel J., Sun, Hui B., Mason, Jeffrey B., Haskins, Mark E., Richardson, Dean W., Schuchman, Edward H.
Publicado em 2013

Intra-articular Enzyme Replacement Therapy with rhIDUA is Safe, Well-Tolerated, and Reduces Articular GAG Storage in the Canine Model of Mucopolysaccharidosis Type I

Por Wang, Raymond Y, Aminian, Afshin, McEntee, Michael F, Kan, Shih-Hsin, Simonaro, Calogera M, Lamanna, William, Lawrence, Roger, Ellinwood, N. Matthew, Guerra, Catalina, Le, Steven Q, Dickson, Patricia I, Esko, Jeffrey D
Publicado em 2014

Systemic ceramide accumulation leads to severe and varied pathological consequences

Por Alayoubi, Abdulfatah M, Wang, James C M, Au, Bryan C Y, Carpentier, Stéphane, Garcia, Virginie, Dworski, Shaalee, El-Ghamrasni, Samah, Kirouac, Kevin N, Exertier, Mathilde J, Xiong, Zi Jian, Privé, Gilbert G, Simonaro, Calogera M, Casas, Josefina, Fabrias, Gemma, Schuchman, Edward H, Turner, Patricia V, Hakem, Razqallah, Levade, Thierry, Medin, Jeffrey A
Publicado em 2013