Mechanism of Glycosaminoglycan-Mediated Bone and Joint Disease : Implications for the Mucopolysaccharidoses and Other Connective Tissue Diseases

We have previously shown that glycosaminoglycan (GAG) storage in animal models of the mucopolysaccharidoses (MPS) leads to inflammation and apoptosis within cartilage. We have now extended these findings to synovial tissue and further explored the mechanism underlying GAG-mediated disease. Analysis...

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Main Authors: Simonaro, Calogera M., D’Angelo, Marina, He, Xingxuan, Eliyahu, Efrat, Shtraizent, Nataly, Haskins, Mark E., Schuchman, Edward H.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2008
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189614/
https://ncbi.nlm.nih.gov/pubmed/18079441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070564
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