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Identification of Cystatin SA as a Novel Inhibitor of Acid Ceramidase

Autoproteolytic cleavage of the inactive acid ceramidase (AC) precursor into the active heterodimer exposes a free cysteine residue, leading us to study whether AC could be regulated by one or more members of the cystatin family. Co-expression of the full-length AC and cystatin SA (cysSA) cDNAs led...

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Autores principales: Eliyahu, Efrat, Shtraizent, Nataly, He, Xingxuan, Chen, Dafna, Shalgi, Ruth, Schuchman, Edward H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195560/
https://ncbi.nlm.nih.gov/pubmed/21846728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.260372
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