Pentosan Polysulfate: A Novel Therapy for the Mucopolysaccharidoses

BACKGROUND: Pentosan polysulfate (PPS) is an FDA-approved, oral medication with anti-inflammatory and pro-chondrogenic properties. We have previously shown that animal models of the mucopolysaccharidoses (MPS) exhibit significant inflammatory disease, contributing to cartilage degeneration. Enzyme r...

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Detalhes bibliográficos
Main Authors: Schuchman, Edward H., Ge, Yi, Lai, Alon, Borisov, Yury, Faillace, Meghan, Eliyahu, Efrat, He, Xingxuan, Iatridis, James, Vlassara, Helen, Striker, Gary, Simonaro, Calogera M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554761/
https://ncbi.nlm.nih.gov/pubmed/23365668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054459
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