Pentosan Polysulfate: Oral Versus Subcutaneous Injection in Mucopolysaccharidosis Type I Dogs

BACKGROUND: We previously demonstrated the therapeutic benefits of pentosan polysulfate (PPS) in a rat model of mucopolysaccharidosis (MPS) type VI. Reduction of inflammation, reduction of glycosaminoglycan (GAG) storage, and improvement in the skeletal phenotype were shown. Herein, we evaluate the...

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Vydáno v:PLoS One
Hlavní autoři: Simonaro, Calogera M., Tomatsu, Shunji, Sikora, Tracy, Kubaski, Francyne, Frohbergh, Michael, Guevara, Johana M., Wang, Raymond Y., Vera, Moin, Kang, Jennifer L., Smith, Lachlan J., Schuchman, Edward H., Haskins, Mark E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4827827/
https://ncbi.nlm.nih.gov/pubmed/27064989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153136
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