The structure of a bacterial DUF199 / WhiA protein: domestication of an invasive endonuclease

Por Kaiser, Brett K., Clifton, Matthew C., Shen, Betty W., Stoddard, Barry L.
Publicado em 2009

The Structural Basis of Asymmetry in DNA Binding and Cleavage as Exhibited by the I-SmaMI LAGLIDADG Meganuclease

Por Shen, Betty W., Lambert, Abigail, Walker, Bradley C., Stoddard, Barry L., Kaiser, Brett K.
Publicado no J Mol Biol (2015)

Control of repeat protein curvature by computational protein design

Por Park, Keunwan, Shen, Betty W., Parmeggiani, Fabio, Huang, Po-Ssu, Stoddard, Barry L., Baker, David
Publicado no Nat Struct Mol Biol (2015)

DNA recognition by the SwaI restriction endonuclease involves unusual distortion of an 8 base pair A:T-rich target

Por Shen, Betty W., Heiter, Daniel F., Lunnen, Keith D., Wilson, Geoffrey G., Stoddard, Barry L.
Publicado no Nucleic Acids Res (2017)

Thermodynamics of DNA target site recognition by homing endonucleases

Por Eastberg, Jennifer H., Smith, Audrey McConnell, Zhao, Lei, Ashworth, Justin, Shen, Betty W., Stoddard, Barry L.
Publicado em 2007

Expanding LAGLIDADG endonuclease scaffold diversity by rapidly surveying evolutionary sequence space

Por Jacoby, Kyle, Metzger, Michael, Shen, Betty W., Certo, Michael T., Jarjour, Jordan, Stoddard, Barry L., Scharenberg, Andrew M.
Publicado em 2012

Characterization and crystal structure of the type IIG restriction endonuclease RM.BpuSI

Por Shen, Betty W., Xu, Derrick, Chan, Siu-Hong, Zheng, Yu, Zhu, Zhenyu, Xu, Shuang-yong, Stoddard, Barry L.
Publicado em 2011

The tertiary structure and domain organization of coagulation factor VIII

Por Shen, Betty W., Spiegel, Paul Clint, Chang, Chong-Hwan, Huh, Jae-Wook, Lee, Jung-Sik, Kim, Jeanman, Kim, Young-Ho, Stoddard, Barry L.
Publicado em 2008

Increased Diels-Alderase Activity through Foldit Player Guided Backbone Remodeling

Por Eiben, Christopher B., Siegel, Justin B., Bale, Jacob B., Cooper, Seth, Khatib, Firas, Shen, Betty W., Players, Foldit, Stoddard, Barry L., Popovic, Zoran, Baker, David
Publicado em 2012

Indirect DNA sequence recognition and its impact on nuclease cleavage activity

Por Lambert, Abigail R., Hallinan, Jazmine P., Shen, Betty W., Chik, Jennifer K., Bolduc, Jill M., Kulshina, Nadia, Robins, Lori I., Kaiser, Brett K., Jarjour, Jordan, Havens, Kyle, Scharenberg, Andrew M., Stoddard, Barry L.
Publicado no Structure (2016)

A computationally designed inhibitor of an Epstein-Barr viral Bcl-2 protein induces apoptosis in infected cells

Por Procko, Erik, Berguig, Geoffrey Y., Shen, Betty W., Song, Yifan, Frayo, Shani, Convertine, Anthony J., Margineantu, Daciana, Booth, Garrett, Correia, Bruno E., Cheng, Yuanhua, Schief, William R., Hockenbery, David M., Press, Oliver W., Stoddard, Barry L., Stayton, Patrick S., Baker, David
Publicado em 2014

Computational protein design enables a novel one-carbon assimilation pathway

Por Siegel, Justin B., Smith, Amanda Lee, Poust, Sean, Wargacki, Adam J., Bar-Even, Arren, Louw, Catherine, Shen, Betty W., Eiben, Christopher B., Tran, Huu M., Noor, Elad, Gallaher, Jasmine L., Bale, Jacob, Yoshikuni, Yasuo, Gelb, Michael H., Keasling, Jay D., Stoddard, Barry L., Lidstrom, Mary E., Baker, David
Publicado no Proc Natl Acad Sci U S A (2015)

Computationally designed high specificity inhibitors delineate the roles of BCL2 family proteins in cancer

Por Berger, Stephanie, Procko, Erik, Margineantu, Daciana, Lee, Erinna F, Shen, Betty W, Zelter, Alex, Silva, Daniel-Adriano, Chawla, Kusum, Herold, Marco J, Garnier, Jean-Marc, Johnson, Richard, MacCoss, Michael J, Lessene, Guillaume, Davis, Trisha N, Stayton, Patrick S, Stoddard, Barry L, Fairlie, W Douglas, Hockenbery, David M, Baker, David
Publicado no eLife (2016)