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The tertiary structure and domain organization of coagulation factor VIII
Factor VIII (fVIII) is a serum protein in the coagulation cascade that nucleates the assembly of a membrane-bound protease complex on the surface of activated platelets at the site of a vascular injury. Hemophilia A is caused by a variety of mutations in the factor VIII gene and typically requires r...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Hematology
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2214755/ https://ncbi.nlm.nih.gov/pubmed/17965321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-08-109918 |
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