Molecular coevolution of coagulation factor VIII and von Willebrand factor

Ancestral sequence reconstruction provides a unique platform for investigating the molecular evolution of single gene products and recently has shown success in engineering advanced biological therapeutics. To date, the coevolution of proteins within complexes and protein–protein interactions is mos...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Zakas, Philip M., Coyle, Christopher W., Brehm, Anja, Bayer, Marion, Solecka-Witulska, Barbara, Radford, Caelan E., Brown, Christine, Nesbitt, Kate, Dwyer, Courtney, Kannicht, Christoph, Spencer, H. Trent, Gaucher, Eric A., Doering, Christopher B., Lillicrap, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876868/
https://ncbi.nlm.nih.gov/pubmed/33560395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002971
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