Molecular coevolution of coagulation factor VIII and von Willebrand factor

Ancestral sequence reconstruction provides a unique platform for investigating the molecular evolution of single gene products and recently has shown success in engineering advanced biological therapeutics. To date, the coevolution of proteins within complexes and protein–protein interactions is mos...

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Bibliografske podrobnosti
izdano v:Blood Adv
Main Authors: Zakas, Philip M., Coyle, Christopher W., Brehm, Anja, Bayer, Marion, Solecka-Witulska, Barbara, Radford, Caelan E., Brown, Christine, Nesbitt, Kate, Dwyer, Courtney, Kannicht, Christoph, Spencer, H. Trent, Gaucher, Eric A., Doering, Christopher B., Lillicrap, David
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2021
Teme:
Thrombosis and Hemostasis
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876868/
https://ncbi.nlm.nih.gov/pubmed/33560395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002971
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