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Gut dysbiosis modulates the immune response to factor VIII in murine hemophilia A

The development of neutralizing FVIII antibodies is the most serious complication of hemophilia A treatment. The currently known patient- and treatment-related risk factors for inhibitor development do not accurately predict this adverse event in all patients. The composition of the gut microbiota h...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Tarrant, Julie, Cormier, Matthew, Nesbitt, Kate, Dwyer, Courtney, Hough, Christine, Lillicrap, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7322952/
https://ncbi.nlm.nih.gov/pubmed/32556285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001144
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