Molecular coevolution of coagulation factor VIII and von Willebrand factor

Ancestral sequence reconstruction provides a unique platform for investigating the molecular evolution of single gene products and recently has shown success in engineering advanced biological therapeutics. To date, the coevolution of proteins within complexes and protein–protein interactions is mos...

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Vydáno v:Blood Adv
Hlavní autoři: Zakas, Philip M., Coyle, Christopher W., Brehm, Anja, Bayer, Marion, Solecka-Witulska, Barbara, Radford, Caelan E., Brown, Christine, Nesbitt, Kate, Dwyer, Courtney, Kannicht, Christoph, Spencer, H. Trent, Gaucher, Eric A., Doering, Christopher B., Lillicrap, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2021
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876868/
https://ncbi.nlm.nih.gov/pubmed/33560395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002971
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