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Solution structure of the major factor VIII binding region on von Willebrand factor

Although much of the function of von Willebrand factor (VWF) has been revealed, detailed insight into the molecular structure that enables VWF to orchestrate hemostatic processes, in particular factor VIII (FVIII) binding and stabilization in plasma, is lacking. Here, we present the high-resolution...

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Detalhes bibliográficos
Main Authors: Shiltagh, Nuha, Kirkpatrick, John, Cabrita, Lisa D., McKinnon, Tom A. J., Thalassinos, Konstantinos, Tuddenham, Edward G. D., Hansen, D. Flemming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073327/
https://ncbi.nlm.nih.gov/pubmed/24700780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517086
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