Solution structure of the major factor VIII binding region on von Willebrand factor

Although much of the function of von Willebrand factor (VWF) has been revealed, detailed insight into the molecular structure that enables VWF to orchestrate hemostatic processes, in particular factor VIII (FVIII) binding and stabilization in plasma, is lacking. Here, we present the high-resolution...

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Main Authors: Shiltagh, Nuha, Kirkpatrick, John, Cabrita, Lisa D., McKinnon, Tom A. J., Thalassinos, Konstantinos, Tuddenham, Edward G. D., Hansen, D. Flemming
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Hematology 2014
Ábhair:
Thrombosis and Hemostasis
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4073327/
https://ncbi.nlm.nih.gov/pubmed/24700780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-517086
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