Molecular coevolution of coagulation factor VIII and von Willebrand factor

Ancestral sequence reconstruction provides a unique platform for investigating the molecular evolution of single gene products and recently has shown success in engineering advanced biological therapeutics. To date, the coevolution of proteins within complexes and protein–protein interactions is mos...

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Bibliografische gegevens
Gepubliceerd in:Blood Adv
Hoofdauteurs: Zakas, Philip M., Coyle, Christopher W., Brehm, Anja, Bayer, Marion, Solecka-Witulska, Barbara, Radford, Caelan E., Brown, Christine, Nesbitt, Kate, Dwyer, Courtney, Kannicht, Christoph, Spencer, H. Trent, Gaucher, Eric A., Doering, Christopher B., Lillicrap, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2021
Onderwerpen:
Thrombosis and Hemostasis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876868/
https://ncbi.nlm.nih.gov/pubmed/33560395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002971
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