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Control of repeat protein curvature by computational protein design
Shape complementarity is an important component of molecular recognition, and the ability to precisely adjust the shape of a binding scaffold to match a target of interest would greatly facilitate the creation of high affinity protein reagents and therapeutics. Here we describe a general approach to...
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318719/ https://ncbi.nlm.nih.gov/pubmed/25580576 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2938 |
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