Elfin UI: A Graphical Interface for Protein Design With Modular Building Blocks

Por Yeh, Chun-Ting, Obendorf, Leon, Parmeggiani, Fabio
Publicado no Front Bioeng Biotechnol (2020)

Discovery and Investigation of Mutase-like Activity in a Phenylalanine Ammonia Lyase from Anabaena variabilis

Por Weise, Nicholas J., Parmeggiani, Fabio, Ahmed, Syed T., Turner, Nicholas J.
Publicado no Top Catal (2018)

A Substitution in the Fingers Domain of DNA Polymerase δ Reduces Fidelity by Altering Nucleotide Discrimination in the Catalytic Site

Por Prindle, Marc J., Schmitt, Michael W., Parmeggiani, Fabio, Loeb, Lawrence A.
Publicado em 2013

Synthesis of d- and l-Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process**

Por Parmeggiani, Fabio, Lovelock, Sarah L, Weise, Nicholas J, Ahmed, Syed T, Turner, Nicholas J
Publicado no Angew Chem Int Ed Engl (2015)

Synthesis of d‐ and l‐Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process

Por Parmeggiani, Fabio, Lovelock, Sarah L., Weise, Nicholas J., Ahmed, Syed T., Turner, Nicholas J.
Publicado no Angew Chem Weinheim Bergstr Ger (2015)

Extreme stability in de novo-designed repeat arrays is determined by unusually stable short-range interactions

Por Geiger-Schuller, Kathryn, Sforza, Kevin, Yuhas, Max, Parmeggiani, Fabio, Baker, David, Barrick, Doug
Publicado no Proc Natl Acad Sci U S A (2018)

One-Pot Multi-Enzymatic Synthesis of the Four Stereoisomers of 4-Methylheptan-3-ol

Por Brenna, Elisabetta, Crotti, Michele, Gatti, Francesco G., Monti, Daniela, Parmeggiani, Fabio, Pugliese, Andrea
Publicado no Molecules (2017)

One‐Pot Synthesis of Chiral N‐Arylamines by Combining Biocatalytic Aminations with Buchwald–Hartwig N‐Arylation

Por Cosgrove, Sebastian C., Thompson, Matthew P., Ahmed, Syed T., Parmeggiani, Fabio, Turner, Nicholas J.
Publicado no Angew Chem Int Ed Engl (2020)

Characterization of a Putrescine Transaminase From Pseudomonas putida and its Application to the Synthesis of Benzylamine Derivatives

Por Galman, James L., Gahloth, Deepankar, Parmeggiani, Fabio, Slabu, Iustina, Leys, David, Turner, Nicholas J.
Publicado no Front Bioeng Biotechnol (2018)

Control of repeat protein curvature by computational protein design

Por Park, Keunwan, Shen, Betty W., Parmeggiani, Fabio, Huang, Po-Ssu, Stoddard, Barry L., Baker, David
Publicado no Nat Struct Mol Biol (2015)

De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy

Por Huang, Po-Ssu, Feldmeier, Kaspar, Parmeggiani, Fabio, Velasco, D. Alejandro Fernandez, Höcker, Birte, Baker, David
Publicado no Nat Chem Biol (2015)

Rational design of alpha-helical tandem repeat proteins with closed architectures

Por Doyle, Lindsey, Hallinan, Jazmine, Bolduc, Jill, Parmeggiani, Fabio, Baker, David, Stoddard, Barry L., Bradley, Philip
Publicado no Nature (2015)

Optimization of designed armadillo repeat proteins by molecular dynamics simulations and NMR spectroscopy

Por Alfarano, Pietro, Varadamsetty, Gautham, Ewald, Christina, Parmeggiani, Fabio, Pellarin, Riccardo, Zerbe, Oliver, Plückthun, Andreas, Caflisch, Amedeo
Publicado em 2012

Stereoselectivity Switch in the Reduction of α-Alkyl-β-Arylenones by Structure-Guided Designed Variants of the Ene Reductase OYE1

Por Crotti, Michele, Parmeggiani, Fabio, Ferrandi, Erica Elisa, Gatti, Francesco G., Sacchetti, Alessandro, Riva, Sergio, Brenna, Elisabetta, Monti, Daniela
Publicado no Front Bioeng Biotechnol (2019)

Enzymatic Building‐Block Synthesis for Solid‐Phase Automated Glycan Assembly

Por Marchesi, Andrea, Parmeggiani, Fabio, Louçano, João, Mattey, Ashley P., Huang, Kun, Gupta, Tanistha, Salwiczek, Mario, Flitsch, Sabine L.
Publicado no Angew Chem Int Ed Engl (2020)

Zymophore identification enables the discovery of novel phenylalanine ammonia lyase enzymes

Por Weise, Nicholas J., Ahmed, Syed T., Parmeggiani, Fabio, Galman, James L., Dunstan, Mark S., Charnock, Simon J., Leys, David, Turner, Nicholas J.
Publicado no Sci Rep (2017)

Exploring the repeat protein universe through computational protein design

Por Brunette, TJ, Parmeggiani, Fabio, Huang, Po-Ssu, Bhabha, Gira, Ekiert, Damian C., Tsutakawa, Susan E., Hura, Greg L., Tainer, John A., Baker, David
Publicado no Nature (2015)

Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases

Por Baxter, Sarah, Lambert, Abigail R., Kuhar, Ryan, Jarjour, Jordan, Kulshina, Nadia, Parmeggiani, Fabio, Danaher, Patrick, Gano, Jacob, Baker, David, Stoddard, Barry L., Scharenberg, Andrew M.
Publicado em 2012

Computational design of a homotrimeric metalloprotein with a trisbipyridyl core

Por Mills, Jeremy H., Sheffler, William, Ener, Maraia E., Almhjell, Patrick J., Oberdorfer, Gustav, Pereira, José Henrique, Parmeggiani, Fabio, Sankaran, Banumathi, Zwart, Peter H., Baker, David
Publicado no Proc Natl Acad Sci U S A (2016)

A General Computational Approach for Repeat Protein Design

Por Parmeggiani, Fabio, Huang, Po-Ssu, Vorobiev, Sergey, Xiao, Rong, Park, Keunwan, Caprari, Silvia, Su, Min, Jayaraman, Seetharaman, Mao, Lei, Janjua, Haleema, Montelione, Gaetano T., Hunt, John, Baker, David
Publicado no J Mol Biol (2014)