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Rational design of alpha-helical tandem repeat proteins with closed architectures

Tandem repeat proteins, which are formed by repetition of modular units of protein sequence and structure, play important biological roles as macromolecular binding and scaffolding domains, enzymes, and building blocks for the assembly of fibrous materials(1,2). The modular nature of repeat proteins...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Doyle, Lindsey, Hallinan, Jazmine, Bolduc, Jill, Parmeggiani, Fabio, Baker, David, Stoddard, Barry L., Bradley, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4727831/
https://ncbi.nlm.nih.gov/pubmed/26675735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16191
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