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Engineering and functionalization of large circular tandem repeat protein nanoparticles

Protein engineering has enabled the design of molecular scaffolds that display a wide variety of sizes, shapes, symmetry and subunit composition. Symmetric protein-based nanoparticles that display multiple protein domains can exhibit enhanced functional properties due to increased avidity and improv...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Correnti, Colin E., Hallinan, Jazmine P., Doyle, Lindsey A., Ruff, Raymond O., Jaeger-Ruckstuhl, Carla A., Xu, Yuexin, Shen, Betty W., Qu, Amanda, Polkinghorn, Caley, Friend, Della J., Bandaranayake, Ashok D., Riddell, Stanley R., Kaiser, Brett K., Stoddard, Barry L., Bradley, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7336869/
https://ncbi.nlm.nih.gov/pubmed/32203491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0397-5
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