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Stereoselectivity Switch in the Reduction of α-Alkyl-β-Arylenones by Structure-Guided Designed Variants of the Ene Reductase OYE1

Ene reductases from the Old Yellow Enzyme (OYE) family are industrially interesting enzymes for the biocatalytic asymmetric reduction of alkenes. To access both enantiomers of the target reduced products, stereocomplementary pairs of OYE enzymes are necessary, but their natural occurrence is quite l...

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Detaylı Bibliyografya
Yayımlandı:Front Bioeng Biotechnol
Asıl Yazarlar: Crotti, Michele, Parmeggiani, Fabio, Ferrandi, Erica Elisa, Gatti, Francesco G., Sacchetti, Alessandro, Riva, Sergio, Brenna, Elisabetta, Monti, Daniela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497740/
https://ncbi.nlm.nih.gov/pubmed/31080798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00089
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