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Synthesis of d‐ and l‐Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process
The synthesis of substituted d‐phenylalanines in high yield and excellent optical purity, starting from inexpensive cinnamic acids, has been achieved with a novel one‐pot approach by coupling phenylalanine ammonia lyase (PAL) amination with a chemoenzymatic deracemization (based on stereoselective o...
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| Udgivet i: | Angew Chem Weinheim Bergstr Ger |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
WILEY‐VCH Verlag
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4955227/ https://ncbi.nlm.nih.gov/pubmed/27478261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ange.201410670 |
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