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Synthesis of d‐ and l‐Phenylalanine Derivatives by Phenylalanine Ammonia Lyases: A Multienzymatic Cascade Process

The synthesis of substituted d‐phenylalanines in high yield and excellent optical purity, starting from inexpensive cinnamic acids, has been achieved with a novel one‐pot approach by coupling phenylalanine ammonia lyase (PAL) amination with a chemoenzymatic deracemization (based on stereoselective o...

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Bibliografske podrobnosti
izdano v:Angew Chem Weinheim Bergstr Ger
Main Authors: Parmeggiani, Fabio, Lovelock, Sarah L., Weise, Nicholas J., Ahmed, Syed T., Turner, Nicholas J.
Format: Artigo
Jezik:Inglês
Izdano: WILEY‐VCH Verlag 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4955227/
https://ncbi.nlm.nih.gov/pubmed/27478261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ange.201410670
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