Combined obstructive hypertrophic cardiomyopathy and double outlet right ventricle in an infant with Down syndrome

Por Ghimire, Laxmi, Tawffik, Ossama, Schroeder, Valerie A.
Publicado em 2013

Selective Gelatinase Inhibitor Neuroprotective Agents Cross the Blood-Brain Barrier

Por Gooyit, Major, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Publicado em 2012

Selective Water-Soluble Gelatinase Inhibitor Prodrugs

Por Gooyit, Major, Lee, Mijoon, Schroeder, Valerie A., Ikejiri, Masahiro, Suckow, Mark A., Mobashery, Shahriar, Chang, Mayland
Publicado em 2011

In Vitro and In Vivo Synergy of the Oxadiazole Class of Antibacterials with β-Lactams

Por Janardhanan, Jeshina, Meisel, Jayda E., Ding, Derong, Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Publicado no Antimicrob Agents Chemother (2016)

O-Phenyl Carbamate and Phenyl Urea Thiiranes as Selective Matrix Metalloproteinase-2 Inhibitors that Cross the Blood-Brain Barrier

Por Gooyit, Major, Song, Wei, Mahasenan, Kiran V., Lichtenwalter, Katerina, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Publicado em 2013

In Search of Selectivity in Inhibition of ADAM10

Por Mahasenan, Kiran V., Ding, Derong, Gao, Ming, Nguyen, Trung T., Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Chang, Mayland, Mobashery, Shahriar
Publicado no ACS Med Chem Lett (2018)

ADP-Ribosylation Factor 6 Regulates Tumorigenic and Invasive Properties In vivo

Por Muralidharan-Chari, Vandhana, Hoover, Holly, Clancy, James, Schweitzer, Jill, Suckow, Mark A., Schroeder, Valerie, Castellino, Francis J., Schorey, Jeffrey S., D’Souza-Schorey, Crislyn
Publicado em 2009

Water-Soluble MMP-9 Inhibitor Prodrug Generates Active Metabolites That Cross the Blood–Brain Barrier

Por Song, Wei, Peng, Zhihong, Gooyit, Major, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Lee, Mijoon, Ikejiri, Masajiro, Cui, Jiankun, Gu, Zezong, Chang, Mayland
Publicado em 2013

Structure–Activity Relationship for the 4(3H)-Quinazolinone Antibacterials

Por Bouley, Renee, Ding, Derong, Peng, Zhihong, Bastian, Maria, Lastochkin, Elena, Song, Wei, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Mobashery, Shahriar, Chang, Mayland
Publicado no J Med Chem (2016)

Expression of active matrix metalloproteinase-9 as a likely contributor to the clinical failure of aclerastide in treatment of diabetic foot ulcers

Por Nguyen, Trung T., Ding, Derong, Wolter, William R., Champion, Matthew M., Hesek, Dusan, Lee, Mijoon, Pérez, Rocio L., Schroeder, Valerie A., Suckow, Mark A., Mobashery, Shahriar, Chang, Mayland
Publicado no Eur J Pharmacol (2018)

Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse

Por Semple, Bridgette D., Noble-Haeusslein, Linda J., Gooyit, Major, Tercovich, Kayleen G., Peng, Zhihong, Nguyen, Trung T., Schroeder, Valerie A., Suckow, Mark A., Chang, Mayland, Raber, Jacob, Trivedi, Alpa
Publicado no PLoS One (2015)

Exploitation of Conformational Dynamics in Imparting Selective Inhibition for Related Matrix Metalloproteinases

Por Mahasenan, Kiran V., Bastian, Maria, Gao, Ming, Frost, Emma, Ding, Derong, Zorina-Lichtenwalter, Katerina, Jacobs, John, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Chang, Mayland, Mobashery, Shahriar
Publicado no ACS Med Chem Lett (2017)

Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

Por Gonzales, Patrick R., Pesesky, Mitchell W., Bouley, Renee, Ballard, Anna, Biddy, Brent A., Suckow, Mark A., Wolter, William R., Schroeder, Valerie A., Burnham, Carey-Ann D., Mobashery, Shahriar, Chang, Mayland, Dantas, Gautam
Publicado no Nat Chem Biol (2015)

The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

Por Janardhanan, Jeshina, Bouley, Renee, Martínez-Caballero, Siseth, Peng, Zhihong, Batuecas-Mordillo, Mayte, Meisel, Jayda E., Ding, Derong, Schroeder, Valerie A., Wolter, William R., Mahasenan, Kiran V., Hermoso, Juan A., Mobashery, Shahriar, Chang, Mayland
Publicado no Antimicrob Agents Chemother (2019)

Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one

Por Bouley, Renee, Kumarasiri, Malika, Peng, Zhihong, Otero, Lisandro H., Song, Wei, Suckow, Mark A., Schroeder, Valerie A., Wolter, William R., Lastochkin, Elena, Antunes, Nuno T., Pi, Hualiang, Vakulenko, Sergei, Hermoso, Juan A., Chang, Mayland, Mobashery, Shahriar
Publicado no J Am Chem Soc (2015)

Water-Soluble MMP-9 Inhibitor Reduces Lesion Volume after Severe Traumatic Brain Injury

Por Lee, Mijoon, Chen, Zhenzhou, Tomlinson, Brittany N., Gooyit, Major, Hesek, Dusan, Juárez, María Raquel, Nizam, Rasheeq, Boggess, Bill, Lastochkin, Elena, Schroeder, Valerie A., Wolter, William R., Suckow, Mark A., Cui, Jiancun, Mobashery, Shahriar, Gu, Zezong, Chang, Mayland
Publicado no ACS Chem Neurosci (2015)

Structure–Activity Relationship for the Oxadiazole Class of Antibiotics

Por Spink, Edward, Ding, Derong, Peng, Zhihong, Boudreau, Marc A., Leemans, Erika, Lastochkin, Elena, Song, Wei, Lichtenwalter, Katerina, O’Daniel, Peter I., Testero, Sebastian A., Pi, Hualiang, Schroeder, Valerie A., Wolter, William R., Antunes, Nuno T., Suckow, Mark A., Vakulenko, Sergei, Chang, Mayland, Mobashery, Shahriar
Publicado no J Med Chem (2015)

Selective Inhibition of Matrix Metalloproteinase-9 Attenuates Secondary Damage Resulting from Severe Traumatic Brain Injury

Por Hadass, Orr, Tomlinson, Brittany N., Gooyit, Major, Chen, Shanyan, Purdy, Justin J., Walker, Jennifer M., Zhang, Chunyang, Giritharan, Andrew B., Purnell, Whitley, Robinson, Christopher R., Shin, Dmitriy, Schroeder, Valerie A., Suckow, Mark A., Simonyi, Agnes, Y. Sun, Grace, Mobashery, Shahriar, Cui, Jiankun, Chang, Mayland, Gu, Zezong
Publicado em 2013

Discovery of a New Class of Non-β-lactam Inhibitors of Penicillin-Binding Proteins with Gram-Positive Antibacterial Activity

Por O’Daniel, Peter I., Peng, Zhihong, Pi, Hualiang, Testero, Sebastian A., Ding, Derong, Spink, Edward, Leemans, Erika, Boudreau, Marc A., Yamaguchi, Takao, Schroeder, Valerie A., Wolter, William R., Llarrull, Leticia I., Song, Wei, Lastochkin, Elena, Kumarasiri, Malika, Antunes, Nuno T., Espahbodi, Mana, Lichtenwalter, Katerina, Suckow, Mark A., Vakulenko, Sergei, Mobashery, Shahriar, Chang, Mayland
Publicado em 2014