Llwytho...

Selective Water-Soluble Gelatinase Inhibitor Prodrugs

SB-3CT (1), a selective and potent thiirane-based gelatinase inhibitor, is effective in animal models of cancer metastasis and stroke; however, it is limited by poor aqueous solubility and extensive metabolism. We addressed these issues by blocking the primary site of metabolism and capitalizing on...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gooyit, Major, Lee, Mijoon, Schroeder, Valerie A., Ikejiri, Masahiro, Suckow, Mark A., Mobashery, Shahriar, Chang, Mayland
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190643/
https://ncbi.nlm.nih.gov/pubmed/21866961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200566e
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