Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse

The gelatinases, matrix metalloproteinases (MMP)-2 and MMP-9, are thought to be key mediators of secondary damage in adult animal models of brain injury. Moreover, an acute increase in these proteases in plasma and brain extracellular fluid of adult patients with moderate-to-severe traumatic brain i...

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Udgivet i:PLoS One
Main Authors: Semple, Bridgette D., Noble-Haeusslein, Linda J., Gooyit, Major, Tercovich, Kayleen G., Peng, Zhihong, Nguyen, Trung T., Schroeder, Valerie A., Suckow, Mark A., Chang, Mayland, Raber, Jacob, Trivedi, Alpa
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4654502/
https://ncbi.nlm.nih.gov/pubmed/26588471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0143386
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