SAR analysis of novel non-peptidic NPBWR1 (GPR7) antagonists

Por Guerrero, Miguel, Urbano, Mariangela, Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Publicado em 2012

Discovery, Design and Synthesis of the First Reported Potent and Selective Sphingosine-1-Phosphate 4 (S1P(4)) Receptor Antagonists

Por Guerrero, Miguel, Urbano, Mariangela, Velaparthi, Subash, Zhao, Jian, Schaeffer, MarieTherese, Brown, Steve, Rosen, Hugh, Roberts, Edward
Publicado em 2011

SAR Analysis of Innovative Selective Small Molecule Antagonists of Sphingosine-1-Phosphate 4 (S1P(4)) Receptor

Por Urbano, Mariangela, Guerrero, Miguel, Zhao, Jian, Velaparthi, Subash, Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Publicado em 2011

Discovery, synthesis and SAR analysis of novel selective small molecule S1P(4)–R agonists based on a (2Z,5Z)-5-((pyrrol-3-yl)methylene)-3-alkyl-2-(alkylimino)thiazolidin-4-one chem...

Por Urbano, Mariangela, Guerrero, Miguel, Velaparthi, Subash, Crisp, Melissa, Chase, Peter, Hodder, Peter, Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Publicado em 2011

Discovery, Design and Synthesis of Novel Potent and Selective Sphingosine-1-Phosphate 4 Receptor (S1P(4)-R) Agonists

Por Guerrero, Miguel, Urbano, Mariangela, Zhao, Jian, Crisp, Melissa, Chase, Peter, Hodder, Peter, Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Publicado em 2011

Ligand-binding pocket shape differences between S1P(1) and S1P(3) determine efficiency of chemical probe identification by uHTS

Por Schürer, Stephan C., Brown, Steven J., Cabrera, Pedro Gonzales, Schaeffer, Marie-Therese, Chapman, Jacqueline, Jo, Euijung, Chase, Peter, Spicer, Tim, Hodder, Peter, Rosen, Hugh
Publicado em 2008

Actions of a picomolar short-acting S1P(1) agonist in S1P(1)-eGFP knock-in mice

Por Cahalan, Stuart M., Gonzalez-Cabrera, Pedro J., Sarkisyan, Gor, Nguyen, Nhan, Schaeffer, Marie-Therese, Huang, Liming, Yeager, Adam, Clemons, Bryan, Scott, Fiona, Rosen, Hugh
Publicado em 2011

Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist

Por Guerrero, Miguel, Poddutoori, Ramulu, Urbano, Mariangela, Peng, Xuemei, Spicer, Timothy P., Chase, Peter S., Hodder, Peter S., Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Publicado em 2013

A Sphingosine 1-phosphate receptor 2 selective allosteric agonist

Por Satsu, Hideo, Schaeffer, Marie-Therese, Guerrero, Miguel, Saldana, Adrian, Eberhart, Christina, Hodder, Peter, Cayanan, Charmagne, Schürer, Stephan, Bhhatarai, Barun, Roberts, Ed, Rosen, Hugh, Brown, Steven J.
Publicado em 2013

Design, synthesis and SAR analysis of novel potent and selective small molecule antagonists of NPBWR1 (GPR7)

Por Urbano, Mariangela, Guerrero, Miguel, Zhao, Jian, Velaparthi, Subash, Saldanha, S. Adrian, Chase, Peter, Wang, Zhiwei, Civelli, Olivier, Hodder, Peter, Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Publicado em 2012

Full pharmacological efficacy of a novel S1P(1) agonist that does not require S1P-like head-group interactions

Por Gonzalez-Cabrera, Pedro J., Jo, Euijung, Sanna, M. Germana, Brown, Steven, Leaf, Nora, Marsolais, David, Schaeffer, Marie-Therese, Chapman, Jacqueline, Cameron, Michael, Guerrero, Miguel, Roberts, Edward, Rosen, Hugh
Publicado em 2008