Discovery, design and synthesis of a selective S1P(3) receptor allosteric agonist

Potent and selective S1P(3) receptor (S1P(3)-R) agonists may represent important proof-of-principle tools used to clarify the receptor biological function and assess the therapeutic potential of the S1P(3)-R in cardiovascular, inflammatory and pulmonary diseases. N,N-Dicyclohexyl-5-propylisoxazole-3...

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Detalhes bibliográficos
Main Authors: Guerrero, Miguel, Poddutoori, Ramulu, Urbano, Mariangela, Peng, Xuemei, Spicer, Timothy P., Chase, Peter S., Hodder, Peter S., Schaeffer, Marie-Therese, Brown, Steven, Rosen, Hugh, Roberts, Edward
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3963471/
https://ncbi.nlm.nih.gov/pubmed/24135724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.09.075
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