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Discovery, Design and Synthesis of the First Reported Potent and Selective Sphingosine-1-Phosphate 4 (S1P(4)) Receptor Antagonists
Selective S1P(4) receptor antagonists could be novel therapeutic agents for the treatment of influenza infection in addition to serving as a useful tool for understanding S1P(4) receptor biological functions. 5-(2,5-dichlorophenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide was identified from screen...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3107912/ https://ncbi.nlm.nih.gov/pubmed/21570287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.04.097 |
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