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Actions of a picomolar short-acting S1P(1) agonist in S1P(1)-eGFP knock-in mice
Sphingosine 1-Phosphate Receptor 1 (S1P(1)) plays a critical role in lymphocyte recirculation and is a clinical target for treatment of multiple sclerosis. By generating a short-duration S1P(1) agonist and mice where fluorescently tagged S1P(1) replaces wild-type receptor, we elucidate physiological...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430385/ https://ncbi.nlm.nih.gov/pubmed/21445057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.547 |
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