Lipopolysaccharide-induced Tau Phosphorylation and Kinase Activity: Modulation, but not Mediation, by Corticotropin-Releasing Factor Receptors

por Roe, Allyson D., Staup, Michael A., Serrats, Jordi, Sawchenko, Paul E., Rissman, Robert A.
Publicado em 2011

Brain interstitial oligomeric amyloid β increases with age and is resistant to clearance from brain in a mouse model of Alzheimer's disease

por Takeda, Shuko, Hashimoto, Tadafumi, Roe, Allyson D., Hori, Yukiko, Spires-Jones, Tara L., Hyman, Bradley T.
Publicado em 2013

The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease

por Hopp, Sarah C., Lin, Yang, Oakley, Derek, Roe, Allyson D., DeVos, Sarah L., Hanlon, David, Hyman, Bradley T.
Publicado no J Neuroinflammation (2018)

Increased Tau Phosphorylation and Aggregation in Mice Overexpressing Corticotropin-Releasing Factor

por Campbell, Shannon N., Zhang, Cheng, Monte, Louise, Roe, Allyson D., Rice, Kenner C., Taché, Yvette, Masliah, Eliezer, Rissman, Robert A.
Publicado no J Alzheimers Dis (2015)

Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer’s Disease

por Campbell, Shannon N., Zhang, Cheng, Roe, Allyson D., Lee, Nickey, Lao, Kathleen U., Monte, Louise, Donohue, Michael C., Rissman, Robert A.
Publicado no J Alzheimers Dis (2015)

A flow cytometry–based in vitro assay reveals that formation of apolipoprotein E (ApoE)–amyloid beta complexes depends on ApoE isoform and cell type

por Kara, Eleanna, Marks, Jordan D., Roe, Allyson D., Commins, Caitlin, Fan, Zhanyun, Calvo-Rodriguez, Maria, Wegmann, Susanne, Hudry, Eloise, Hyman, Bradley T.
Publicado no J Biol Chem (2018)

Enhanced Tau Aggregation in the Presence of Amyloid β

por Bennett, Rachel E., DeVos, Sarah L., Dujardin, Simon, Corjuc, Bianca, Gor, Rucha, Gonzalez, Jose, Roe, Allyson D., Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hyman, Bradley T.
Publicado no Am J Pathol (2017)

Longitudinal plasma amyloid beta in Alzheimer’s disease clinical trials

por Donohue, Michael C., Moghadam, Setareh H., Roe, Allyson D., Sun, Chung-Kai, Edland, Steven D., Thomas, Ronald G., Petersen, Ronald C., Sano, Mary, Galasko, Douglas, Aisen, Paul S., Rissman, Robert A.
Publicado no Alzheimers Dement (2014)

Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay

por Kara, Eleanna, Marks, Jordan D., Fan, Zhanyun, Klickstein, Jacob A., Roe, Allyson D., Krogh, Kelly A., Wegmann, Susanne, Maesako, Masato, Luo, Christina C., Mylvaganam, Ravi, Berezovska, Oksana, Hudry, Eloise, Hyman, Bradley T.
Publicado no J Biol Chem (2017)

Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly

por Chhatwal, Jasmeer P., Schultz, Aaron P., Marshall, Gad A., Boot, Brendon, Gomez-Isla, Teresa, Dumurgier, Julien, LaPoint, Molly, Scherzer, Clemens, Roe, Allyson D., Hyman, Bradley T., Sperling, Reisa A., Johnson, Keith A.
Publicado no Neurology (2016)

Reversal of Neurofibrillary Tangles and Tau-Associated Phenotype in the rTgTauEC Model of Early Alzheimer's Disease

por Polydoro, Manuela, de Calignon, Alix, Suárez-Calvet, Marc, Sanchez, Laura, Kay, Kevin R., Nicholls, Samantha B., Roe, Allyson D., Pitstick, Rose, Carlson, George A., Gómez-Isla, Teresa, Spires-Jones, Tara L., Hyman, Bradley T.
Publicado em 2013

Characterization of TauC3 antibody and demonstration of its potential to block tau propagation

por Nicholls, Samantha B., DeVos, Sarah L., Commins, Caitlin, Nobuhara, Chloe, Bennett, Rachel E., Corjuc, Diana L., Maury, Eduardo, Eftekharzadeh, Bahareh, Akingbade, Ololade, Fan, Zhanyun, Roe, Allyson D., Takeda, Shuko, Wegmann, Susanne, Hyman, Bradley T.
Publicado no PLoS One (2017)

Opposing Roles of apolipoprotein E in aging and neurodegeneration

por Hudry, Eloise, Klickstein, Jacob, Cannavo, Claudia, Jackson, Rosemary, Muzikansky, Alona, Gandhi, Sheetal, Urick, David, Sargent, Taylie, Wrobleski, Lauren, Roe, Allyson D, Hou, Steven S, Kuchibhotla, Kishore V, Betensky, Rebecca A, Spires-Jones, Tara, Hyman, Bradley T
Publicado no Life Sci Alliance (2019)

Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer's disease brain

por Takeda, Shuko, Wegmann, Susanne, Cho, Hansang, DeVos, Sarah L., Commins, Caitlin, Roe, Allyson D., Nicholls, Samantha B., Carlson, George A., Pitstick, Rose, Nobuhara, Chloe K., Costantino, Isabel, Frosch, Matthew P., Müller, Daniel J., Irimia, Daniel, Hyman, Bradley T.
Publicado no Nat Commun (2015)

Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo

por DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A, Dooley, Patrick M, Roe, Allyson D, Pitstick, Rose, Irimia, Daniel, Frosch, Matthew P, Carlson, George A, Hyman, Bradley T
Publicado no Brain (2018)

Tau protein liquid–liquid phase separation can initiate tau aggregation

por Wegmann, Susanne, Eftekharzadeh, Bahareh, Tepper, Katharina, Zoltowska, Katarzyna M, Bennett, Rachel E, Dujardin, Simon, Laskowski, Pawel R, MacKenzie, Danny, Kamath, Tarun, Commins, Caitlin, Vanderburg, Charles, Roe, Allyson D, Fan, Zhanyun, Molliex, Amandine M, Hernandez‐Vega, Amayra, Muller, Daniel, Hyman, Anthony A, Mandelkow, Eckhard, Taylor, J Paul, Hyman, Bradley T
Publicado no EMBO J (2018)

Seed-competent HMW tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients

por Takeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E., Trisini Lipsanopoulos, Ana T., Scherzer, Clemens R., Carlson, George A., Pitstick, Rose, Peskind, Elaine R., Raskind, Murray A., Li, Ge, Montine, Thomas J., Frosch, Matthew P., Hyman, Bradley T.
Publicado no Ann Neurol (2016)

Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro

por Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko
Publicado no Am J Pathol (2017)