Retrotransposons: A new and credible source of inherited and somatically acquired hepatocellular carcinoma mutations

Por Rahrmann, Eric P., Largaespada, David A.
Publicado em 2013

Modular assembly of transposon integratable multigene vectors using RecWay assembly

Por Moriarity, Branden S., Rahrmann, Eric P., Keng, Vincent W., Manlove, Luke S., Beckmann, Dominic A., Wolf, Natalie K., Khurshid, Touba, Bell, Jason B., Largaespada, David A.
Publicado em 2013

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve...

Por Keng, Vincent W., Rahrmann, Eric P., Watson, Adrienne L., Tschida, Barbara R., Moertel, Christopher L., Jessen, Walter J., Rizvi, Tilat A., Collins, Margaret H., Ratner, Nancy, Largaespada, David A.
Publicado em 2012

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

Por Rathe, Susan K., Moriarity, Branden S., Stoltenberg, Christopher B., Kurata, Morito, Aumann, Natalie K., Rahrmann, Eric P., Bailey, Natashay J., Melrose, Ellen G., Beckmann, Dominic A., Liska, Chase R., Largaespada, David A.
Publicado em 2014

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST

Por Keng, Vincent W., Watson, Adrienne L., Rahrmann, Eric P., Li, Hua, Tschida, Barbara R., Moriarity, Branden S., Choi, Kwangmin, Rizvi, Tilat A., Collins, Margaret H., Wallace, Margaret R., Ratner, Nancy, Largaespada, David A.
Publicado em 2012

Simple and Efficient Methods for Enrichment and Isolation of Endonuclease Modified Cells

Por Moriarity, Branden S., Rahrmann, Eric P., Beckmann, Dominic A., Conboy, Caitlin B., Watson, Adrienne L., Carlson, Daniel F., Olson, Erik R., Hyland, Kendra A., Fahrenkrug, Scott C., McIvor, R. Scott, Largaespada, David A.
Publicado em 2014

Identification of PDE4D as a proliferation promoting factor in prostate cancer using a Sleeping Beauty transposon based somatic mutagenesis screen

Por Rahrmann, Eric P., Collier, Lara S., Knutson, Todd P., Doyal, Meghan E., Kuslak, Sheri L., Green, Laura E., Malinowski, Rita L., Roethe, Laura, Akagi, Keiko, Waknitz, Michelle, Huang, Wei, Largaespada, David A., Marker, Paul C.
Publicado em 2009

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity

Por Watson, Adrienne L., Anderson, Leah K., Greeley, Andrew D., Keng, Vincent W., Rahrmann, Eric P., Halfond, Amanda L., Powell, Natasha M., Collins, Margaret H., Rizvi, Tilat, Moertel, Christopher L., Ratner, Nancy, Largaespada, David A.
Publicado em 2014

Trp53 Haploinsufficiency Modifies EGFR-Driven Peripheral Nerve Sheath Tumorigenesis

Por Rahrmann, Eric P., Moriarity, Branden S., Otto, George M., Watson, Adrienne L., Choi, Kwangmin, Collins, Margaret H., Wallace, Margaret, Webber, Beau R., Forster, Colleen L., Rizzardi, Anthony E., Schmechel, Stephen C., Ratner, Nancy, Largaespada, David A.
Publicado em 2014

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and genetic pathways driving tumorigenesis

Por Rahrmann, Eric P, Watson, Adrienne L, Keng, Vincent W, Choi, Kwangmin, Moriarity, Branden S, Beckmann, Dominic A, Wolf, Natalie, Sarver, Aaron, Collins, Margaret H, Moertel, Christopher L, Wallace, Margaret R, Gel, Bernat, Serra, Eduard, Ratner, Nancy, Largaespada, David A
Publicado em 2013

Extensive somatic L1 retrotransposition in colorectal tumors

Por Solyom, Szilvia, Ewing, Adam D., Rahrmann, Eric P., Doucet, Tara, Nelson, Heather H., Burns, Michael B., Harris, Reuben S., Sigmon, David F., Casella, Alex, Erlanger, Bracha, Wheelan, Sarah, Upton, Kyle R., Shukla, Ruchi, Faulkner, Geoffrey J., Largaespada, David A., Kazazian, Haig H.
Publicado em 2012

Correction: Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity

Por Watson, Adrienne L., Keller, Bryant J., Williams, Kyle A., Damle, Namrata N., Finnerty, Samuel J., Anderson, Leah K., Greeley, Andrew D., Keng, Vincent W., Rahrmann, Eric P., Halfond, Amanda L., Powell, Natasha M., Collins, Margaret H., Rizvi, Tilat, Moertel, Christopher L., Ratner, Nancy, Largaespada, David A.
Publicado no Oncotarget (2020)

Canonical Wnt/β-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance

Por Watson, Adrienne L., Rahrmann, Eric P., Moriarity, Branden S., Choi, Kwangmin, Conboy, Caitlin B., Greeley, Andrew D., Halfond, Amanda L., Anderson, Leah K., Wahl, Brian R., Keng, Vincent W., Rizzardi, Anthony E., Forster, Colleen L., Collins, Margaret H., Sarver, Aaron L., Wallace, Margaret R., Schmechel, Stephen C., Ratner, Nancy, Largaespada, David A.
Publicado em 2013

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

Por Moriarity, Branden S, Otto, George M, Rahrmann, Eric P, Rathe, Susan K, Wolf, Natalie K, Weg, Madison T, Manlove, Luke A, LaRue, Rebecca S, Temiz, Nuri A, Molyneux, Sam D, Choi, Kwangmin, Holly, Kevin J, Sarver, Aaron L, Scott, Milcah C, Forster, Colleen L, Modiano, Jaime F, Khanna, Chand, Hewitt, Stephen M, Khokha, Rama, Yang, Yi, Gorlick, Richard, Dyer, Michael A, Largaespada, David A
Publicado no Nat Genet (2015)

Sleeping Beauty insertional mutagenesis reveals important genetic drivers of central nervous system embryonal tumors.

Por Beckmann, Pauline J., Larson, Jon D., Larsson, Alex T., Ostergaard, Jason P., Wagner, Sandra, Rahrmann, Eric P., Shamsan, Ghaidan A., Otto, George M., Williams, Rory L., Wang, Jun, Lee, Catherine, Tschida, Barbara R., Das, Paramita, Dubuc, Adrian M., Moriarity, Branden S., Picard, Daniel, Wu, Xiaochong, Rodriguez, Fausto J., Rosemarie, Quincy, Krebs, Ryan D., Molan, Amy M., Demer, Addison M., Frees, Michelle M., Rizzardi, Anthony E., Schmechel, Stephen C., Eberhart, Charles G., Jenkins, Robert B., Wechsler-Reya, Robert J., Odde, David J., Huang, Annie, Taylor, Michael D., Sarver, Aaron L., Largaespada, David A.
Publicado no Cancer Res (2019)