Germline mutagenesis mediated by Sleeping Beauty transposon system in mice

por Takeda, Junji, Keng, Vincent W, Horie, Kyoji
Publicado 2007

Why men are at higher risk for hepatocellular carcinoma?

por Keng, Vincent W., Largaespada, David A., Villanueva, Augusto
Publicado 2012

Mouse Models of Cancer: Sleeping Beauty Transposons for Insertional Mutagenesis Screens and Reverse Genetic Studies

por Tschida, Barbara R., Largaespada, David A., Keng, Vincent W.
Publicado 2014

Translation from nonautonomous type IAP retrotransposon is a critical determinant of transposition activity: Implication for retrotransposon-mediated genome evolution

por Saito, Ei-suke, Keng, Vincent W., Takeda, Junji, Horie, Kyoji
Publicado 2008

Modeling HBx induced hepatocellular carcinoma in mice using the Sleeping Beauty transposon system

por Keng, Vincent W., Tschida, Barbara R., Bell, Jason B., Largaespada, David A.
Publicado 2011

Sleeping Beauty Transposase Has an Affinity for Heterochromatin Conformation

por Ikeda, Ryuji, Kokubu, Chikara, Yusa, Kosuke, Keng, Vincent W., Horie, Kyoji, Takeda, Junji
Publicado 2007

Retrotransposons Influence the Mouse Transcriptome: Implication for the Divergence of Genetic Traits

por Horie, Kyoji, Saito, Ei-suke, Keng, Vincent W., Ikeda, Ryuji, Ishihara, Hiroshi, Takeda, Junji
Publicado 2007

Efficient Transposition of Tol2 in the Mouse Germline

por Keng, Vincent W., Ryan, Barbara J., Wangensteen, Kirk J., Balciunas, Darius, Schmedt, Christian, Ekker, Stephen C., Largaespada, David A.
Publicado 2009

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma

por Chiu, Amy P, Tschida, Barbara R, Lo, Lilian H, Moriarity, Branden S, Rowlands, Dewi K, Largaespada, David A, Keng, Vincent W
Publicado en World J Gastroenterol (2015)

Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor

por Li, Xiao‐Xiao, Zhang, Shi‐Jie, Chiu, Amy P., Lo, Lilian H., Huang, Jian, Rowlands, Dewi K., Wang, Jinhui, Keng, Vincent W.
Publicado en Cancer Med (2018)

Sleeping Beauty Transposon-Based Phenotypic Analysis of Mice: Lack of Arpc3 Results in Defective Trophoblast Outgrowth

por Yae, Kojiro, Keng, Vincent W., Koike, Masato, Yusa, Kosuke, Kouno, Michiyoshi, Uno, Yoshihiro, Kondoh, Gen, Gotow, Takahiro, Uchiyama, Yasuo, Horie, Kyoji, Takeda, Junji
Publicado 2006

Conditional Inactivation of Nf1 and Pten in Schwann Cells Results in Abnormal Neuromuscular Junction Maturation

por Li, Xiao-Xiao, Zhang, Shi-Jie, Chiu, Amy P., Lo, Lilian H., To, Jeffery C., Cui, He-Ning, Rowlands, Dewi K., Keng, Vincent W.
Publicado en G3 (Bethesda) (2018)

Modular assembly of transposon integratable multigene vectors using RecWay assembly

por Moriarity, Branden S., Rahrmann, Eric P., Keng, Vincent W., Manlove, Luke S., Beckmann, Dominic A., Wolf, Natalie K., Khurshid, Touba, Bell, Jason B., Largaespada, David A.
Publicado 2013

Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma

por Riordan, Jesse D., Feddersen, Charlotte R., Tschida, Barbara R., Jackson, Pauline, Keng, Vincent W., Linden, Michael A., Amin, Khalid, Stipp, Christopher S., Largaespada, David A., Dupuy, Adam J.
Publicado en Hepatology (2018)

PTEN and NF1 inactivation in Schwann cells produces a severe phenotype in the peripheral nervous system that promotes the development and malignant progression of peripheral nerve...

por Keng, Vincent W., Rahrmann, Eric P., Watson, Adrienne L., Tschida, Barbara R., Moertel, Christopher L., Jessen, Walter J., Rizvi, Tilat A., Collins, Margaret H., Ratner, Nancy, Largaespada, David A.
Publicado 2012

Characterization of Sleeping Beauty Transposition and Its Application to Genetic Screening in Mice

por Horie, Kyoji, Yusa, Kosuke, Yae, Kojiro, Odajima, Junko, Fischer, Sylvia E. J., Keng, Vincent W., Hayakawa, Tomoko, Mizuno, Sumi, Kondoh, Gen, Ijiri, Takashi, Matsuda, Yoichi, Plasterk, Ronald H. A., Takeda, Junji
Publicado 2003

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST

por Keng, Vincent W., Watson, Adrienne L., Rahrmann, Eric P., Li, Hua, Tschida, Barbara R., Moriarity, Branden S., Choi, Kwangmin, Rizvi, Tilat A., Collins, Margaret H., Wallace, Margaret R., Ratner, Nancy, Largaespada, David A.
Publicado 2012

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity

por Watson, Adrienne L., Anderson, Leah K., Greeley, Andrew D., Keng, Vincent W., Rahrmann, Eric P., Halfond, Amanda L., Powell, Natasha M., Collins, Margaret H., Rizvi, Tilat, Moertel, Christopher L., Ratner, Nancy, Largaespada, David A.
Publicado 2014

A Facile Method for Somatic, Lifelong Manipulation of Multiple Genes in the Mouse Liver

por Wangensteen, Kirk J., Wilber, Andrew, Keng, Vincent W., He, Zhiying, Matise, Ilze, Wangensteen, Laura, Carson, Corey M., Chen, Yixin, Steer, Clifford J., McIvor, R. Scott, Largaespada, David A., Wang, Xin, Ekker, Stephen C.
Publicado en Hepatology (2008)

Identification of Rtl1, a Retrotransposon-Derived Imprinted Gene, as a Novel Driver of Hepatocarcinogenesis

por Riordan, Jesse D., Keng, Vincent W., Tschida, Barbara R., Scheetz, Todd E., Bell, Jason B., Podetz-Pedersen, Kelly M., Moser, Catherine D., Copeland, Neal G., Jenkins, Nancy A., Roberts, Lewis R., Largaespada, David A., Dupuy, Adam J.
Publicado 2013