Targeting of AKT/ERK/CTNNB1 by DAW22 as a potential therapeutic compound for malignant peripheral nerve sheath tumor

Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive form of soft tissue neoplasm with extremely poor prognosis and no effective medical options currently available. MPNSTs can occur either sporadically or in association with the neurofibromatosis type 1 (NF1) syndrome. Importantly, a...

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Bibliographic Details
Published in:Cancer Med
Main Authors: Li, Xiao‐Xiao, Zhang, Shi‐Jie, Chiu, Amy P., Lo, Lilian H., Huang, Jian, Rowlands, Dewi K., Wang, Jinhui, Keng, Vincent W.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Cancer Prevention
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144169/
https://ncbi.nlm.nih.gov/pubmed/30112810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1732
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