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Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma
Most hepatocellular carcinomas (HCCs) develop in a chronically injured liver, yet the extent to which this microenvironment promotes neoplastic transformation or influences selective pressures for genetic drivers of HCC remains unclear. We sought to determine the impact of hepatic injury in an estab...
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| Publicado no: | Hepatology |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826818/ https://ncbi.nlm.nih.gov/pubmed/28961327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29565 |
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