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Mouse Models of Cancer: Sleeping Beauty Transposons for Insertional Mutagenesis Screens and Reverse Genetic Studies

The genetic complexity and heterogeneity of cancer has posed a problem in designing rationally targeted therapies effective in a large proportion of human cancer. Genomic characterization of many cancer types has provided a staggering amount of data that needs to be interpreted to further our unders...

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Detalhes bibliográficos
Main Authors: Tschida, Barbara R., Largaespada, David A., Keng, Vincent W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035448/
https://ncbi.nlm.nih.gov/pubmed/24468652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2014.01.006
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