Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

The evolution from microarrays to transcriptome deep-sequencing (RNA-seq) and from RNA interference to gene knockouts using Clustered Regularly Interspaced Short Palindromic Repeats (CRISPRs) and Transcription Activator-Like Effector Nucleases (TALENs) has provided a new experimental partnership for...

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Main Authors: Rathe, Susan K., Moriarity, Branden S., Stoltenberg, Christopher B., Kurata, Morito, Aumann, Natalie K., Rahrmann, Eric P., Bailey, Natashay J., Melrose, Ellen G., Beckmann, Dominic A., Liska, Chase R., Largaespada, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131221/
https://ncbi.nlm.nih.gov/pubmed/25116387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06048
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