Trp53 Haploinsufficiency Modifies EGFR-Driven Peripheral Nerve Sheath Tumorigenesis

Malignant peripheral nerve sheath tumors (MPNSTs) are genetically diverse, aggressive sarcomas that occur sporadically or in association with neurofibromatosis type 1 syndrome. Reduced TP53 gene expression and amplification/overexpression of the epidermal growth factor receptor (EGFR) gene occur in...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Rahrmann, Eric P., Moriarity, Branden S., Otto, George M., Watson, Adrienne L., Choi, Kwangmin, Collins, Margaret H., Wallace, Margaret, Webber, Beau R., Forster, Colleen L., Rizzardi, Anthony E., Schmechel, Stephen C., Ratner, Nancy, Largaespada, David A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2014
Teme:
Regular Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076465/
https://ncbi.nlm.nih.gov/pubmed/24832557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.04.006
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items