Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemia

Por Mrózek, Krzysztof, Marcucci, Guido, Paschka, Peter, Bloomfield, Clara D.
Publicado em 2008

Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classi...

Por Mrózek, Krzysztof, Marcucci, Guido, Paschka, Peter, Whitman, Susan P., Bloomfield, Clara D.
Publicado em 2007

Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method

Por Liu, Zhongfa, Liu, Shujun, Xie, Zhiliang, Blum, William, Perrotti, Danilo, Paschka, Peter, Klisovic, Rebecca, Byrd, John, Chan, Kenneth K., Marcucci, Guido
Publicado em 2007

Patients With Acute Myeloid Leukemia and RAS Mutations Benefit Most From Postremission High-Dose Cytarabine: A Cancer and Leukemia Group B Study

Por Neubauer, Andreas, Maharry, Kati, Mrózek, Krzysztof, Thiede, Christian, Marcucci, Guido, Paschka, Peter, Mayer, Robert J., Larson, Richard A., Liu, Edison T., Bloomfield, Clara D.
Publicado em 2008

MicroRNA expression-based outcome prediction in acute myeloid leukemia: novel insights through cross-platform integrative analyses

Por Shivarov, Velizar, Dolnik, Anna, Lang, Katharina M., Krönke, Jan, Kuchenbauer, Florian, Paschka, Peter, Gaidzik, Verena I., Döhner, Hartmut, Schlenk, Richard F., Döhner, Konstanze, Bullinger, Lars
Publicado no Haematologica (2016)

Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations

Por Kühn, Michael W.M., Bullinger, Lars, Gröschel, Stefan, Krönke, Jan, Edelmann, Jennifer, Rücker, Frank G., Eiwen, Karina, Paschka, Peter, Gaidzik, Verena I., Holzmann, Karlheinz, Schlenk, Richard F., Döhner, Hartmut, Döhner, Konstanze
Publicado em 2014

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

Por Radmacher, Michael D., Marcucci, Guido, Ruppert, Amy S., Mrózek, Krzysztof, Whitman, Susan P., Vardiman, James W., Paschka, Peter, Vukosavljevic, Tamara, Baldus, Claudia D., Kolitz, Jonathan E., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Publicado em 2006

Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study

Por Whitman, Susan P., Ruppert, Amy S., Marcucci, Guido, Mrózek, Krzysztof, Paschka, Peter, Langer, Christian, Baldus, Claudia D., Wen, Jing, Vukosavljevic, Tamara, Powell, Bayard L., Carroll, Andrew J., Kolitz, Jonathan E., Larson, Richard A., Caligiuri, Michael A., Bloomfield, Clara D.
Publicado em 2007

FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myel...

Por Whitman, Susan P., Ruppert, Amy S., Radmacher, Michael D., Mrózek, Krzysztof, Paschka, Peter, Langer, Christian, Baldus, Claudia D., Wen, Jing, Racke, Frederick, Powell, Bayard L., Kolitz, Jonathan E., Larson, Richard A., Caligiuri, Michael A., Marcucci, Guido, Bloomfield, Clara D.
Publicado em 2008

Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

Por Paschka, Peter, Marcucci, Guido, Ruppert, Amy S., Whitman, Susan P., Mrózek, Krzysztof, Maharry, Kati, Langer, Christian, Baldus, Claudia D., Zhao, Weiqiang, Powell, Bayard L., Baer, Maria R., Carroll, Andrew J., Caligiuri, Michael A., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.
Publicado em 2008

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60...

Por Langer, Christian, Radmacher, Michael D., Ruppert, Amy S., Whitman, Susan P., Paschka, Peter, Mrózek, Krzysztof, Baldus, Claudia D., Vukosavljevic, Tamara, Liu, Chang-Gong, Ross, Mary E., Powell, Bayard L., de la Chapelle, Albert, Kolitz, Jonathan E., Larson, Richard A., Marcucci, Guido, Bloomfield, Clara D.
Publicado em 2008

Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia:...

Por Langer, Christian, Marcucci, Guido, Holland, Kelsi B., Radmacher, Michael D., Maharry, Kati, Paschka, Peter, Whitman, Susan P., Mrózek, Krzysztof, Baldus, Claudia D., Vij, Ravi, Powell, Bayard L., Carroll, Andrew J., Kolitz, Jonathan E., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Publicado em 2009

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia

Por Vey, Norbert, Delaunay, Jacques, Martinelli, Giovanni, Fiedler, Walter, Raffoux, Emmanuel, Prebet, Thomas, Gomez-Roca, Carlos, Papayannidis, Cristina, Kebenko, Maxim, Paschka, Peter, Christen, Randolph, Guarin, Ernesto, Bröske, Ann-Marie, Baehner, Monika, Brewster, Michael, Walz, Antje-Christine, Michielin, Francesca, Runza, Valeria, Meresse, Valerie, Recher, Christian
Publicado no Oncotarget (2016)

Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular F...

Por Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Vukosavljevic, Tamara, Paschka, Peter, Whitman, Susan P., Langer, Christian, Baldus, Claudia D., Liu, Chang-Gong, Ruppert, Amy S., Powell, Bayard L., Carroll, Andrew J., Caligiuri, Michael A., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.
Publicado em 2008

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

Por Metzeler, Klaus H., Hummel, Manuela, Bloomfield, Clara D., Spiekermann, Karsten, Braess, Jan, Sauerland, Maria-Cristina, Heinecke, Achim, Radmacher, Michael, Marcucci, Guido, Whitman, Susan P., Maharry, Kati, Paschka, Peter, Larson, Richard A., Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Buske, Christian
Publicado em 2008

Favorable Prognostic Impact of NPM1 Mutations in Older Patients With Cytogenetically Normal De Novo Acute Myeloid Leukemia and Associated Gene- and MicroRNA-Expression Signatures:...

Por Becker, Heiko, Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Margeson, Dean, Whitman, Susan P., Wu, Yue-Zhong, Schwind, Sebastian, Paschka, Peter, Powell, Bayard L., Carter, Thomas H., Kolitz, Jonathan E., Wetzler, Meir, Carroll, Andrew J., Baer, Maria R., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Publicado em 2010

ASXL1 mutations in younger adult patients with acute myeloid leukemia: a study by the German-Austrian Acute Myeloid Leukemia Study Group

Por Paschka, Peter, Schlenk, Richard F., Gaidzik, Verena I., Herzig, Julia K., Aulitzky, Teresa, Bullinger, Lars, Späth, Daniela, Teleanu, Veronika, Kündgen, Andrea, Köhne, Claus-Henning, Brossart, Peter, Held, Gerhard, Horst, Heinz-A., Ringhoffer, Mark, Götze, Katharina, Nachbaur, David, Kindler, Thomas, Heuser, Michael, Thol, Felicitas, Ganser, Arnold, Döhner, Hartmut, Döhner, Konstanze
Publicado no Haematologica (2015)

Prognostic Significance of Expression of a Single MicroRNA, miR-181a, in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

Por Schwind, Sebastian, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Holland, Kelsi B., Margeson, Dean, Whitman, Susan P., Hickey, Christopher, Becker, Heiko, Metzeler, Klaus H., Paschka, Peter, Baldus, Claudia D., Liu, Shujun, Garzon, Ramiro, Powell, Bayard L., Kolitz, Jonathan E., Carroll, Andrew J., Caligiuri, Michael A., Larson, Richard A., Marcucci, Guido, Bloomfield, Clara D.
Publicado em 2010

Mutations of the Wilms tumor 1 gene (WT1) in older patients with primary cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study

Por Becker, Heiko, Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Margeson, Dean, Whitman, Susan P., Paschka, Peter, Holland, Kelsi B., Schwind, Sebastian, Wu, Yue-Zhong, Powell, Bayard L., Carter, Thomas H., Kolitz, Jonathan E., Wetzler, Meir, Carroll, Andrew J., Baer, Maria R., Moore, Joseph O., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Publicado em 2010

High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations

Por Kühn, Michael W. M., Radtke, Ina, Bullinger, Lars, Goorha, Salil, Cheng, Jinjun, Edelmann, Jennifer, Gohlke, Juliane, Su, Xiaoping, Paschka, Peter, Pounds, Stanley, Krauter, Jürgen, Ganser, Arnold, Quessar, Asmaa, Ribeiro, Raul, Gaidzik, Verena I., Shurtleff, Sheila, Krönke, Jan, Holzmann, Karlheinz, Ma, Jing, Schlenk, Richard F., Rubnitz, Jeffrey E., Döhner, Konstanze, Döhner, Hartmut, Downing, James R.
Publicado em 2012