Advances in molecular genetics and treatment of core-binding factor acute myeloid leukemia

von Mrózek, Krzysztof, Marcucci, Guido, Paschka, Peter, Bloomfield, Clara D.
Veröffentlicht 2008

Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classi...

von Mrózek, Krzysztof, Marcucci, Guido, Paschka, Peter, Whitman, Susan P., Bloomfield, Clara D.
Veröffentlicht 2007

Characterization of in vitro and in vivo hypomethylating effects of decitabine in acute myeloid leukemia by a rapid, specific and sensitive LC-MS/MS method

von Liu, Zhongfa, Liu, Shujun, Xie, Zhiliang, Blum, William, Perrotti, Danilo, Paschka, Peter, Klisovic, Rebecca, Byrd, John, Chan, Kenneth K., Marcucci, Guido
Veröffentlicht 2007

Patients With Acute Myeloid Leukemia and RAS Mutations Benefit Most From Postremission High-Dose Cytarabine: A Cancer and Leukemia Group B Study

von Neubauer, Andreas, Maharry, Kati, Mrózek, Krzysztof, Thiede, Christian, Marcucci, Guido, Paschka, Peter, Mayer, Robert J., Larson, Richard A., Liu, Edison T., Bloomfield, Clara D.
Veröffentlicht 2008

MicroRNA expression-based outcome prediction in acute myeloid leukemia: novel insights through cross-platform integrative analyses

von Shivarov, Velizar, Dolnik, Anna, Lang, Katharina M., Krönke, Jan, Kuchenbauer, Florian, Paschka, Peter, Gaidzik, Verena I., Döhner, Hartmut, Schlenk, Richard F., Döhner, Konstanze, Bullinger, Lars
Veröffentlicht in Haematologica (2016)

Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations

von Kühn, Michael W.M., Bullinger, Lars, Gröschel, Stefan, Krönke, Jan, Edelmann, Jennifer, Rücker, Frank G., Eiwen, Karina, Paschka, Peter, Gaidzik, Verena I., Holzmann, Karlheinz, Schlenk, Richard F., Döhner, Hartmut, Döhner, Konstanze
Veröffentlicht 2014

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

von Radmacher, Michael D., Marcucci, Guido, Ruppert, Amy S., Mrózek, Krzysztof, Whitman, Susan P., Vardiman, James W., Paschka, Peter, Vukosavljevic, Tamara, Baldus, Claudia D., Kolitz, Jonathan E., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Veröffentlicht 2006

Circular RNAs of the nucleophosmin (NPM1) gene in acute myeloid leukemia

von Hirsch, Susanne, Blätte, Tamara J., Grasedieck, Sarah, Cocciardi, Sibylle, Rouhi, Arefeh, Jongen-Lavrencic, Mojca, Paschka, Peter, Krönke, Jan, Gaidzik, Verena I., Döhner, Hartmut, Schlenk, Richard F., Kuchenbauer, Florian, Döhner, Konstanze, Dolnik, Anna, Bullinger, Lars
Veröffentlicht in Haematologica (2017)

Precision oncology for acute myeloid leukemia using a knowledge bank approach

von Gerstung, Moritz, Papaemmanuil, Elli, Martincorena, Inigo, Bullinger, Lars, Gaidzik, Verena I, Paschka, Peter, Heuser, Michael, Thol, Felicitas, Bolli, Niccolo, Ganly, Peter, Ganser, Arnold, McDermott, Ultan, Döhner, Konstanze, Schlenk, Richard F, Döhner, Hartmut, Campbell, Peter J
Veröffentlicht in Nat Genet (2017)

NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia

von Rudorf, Alina, Müller, Tony Andreas, Klingeberg, Cathrin, Kreutmair, Stefanie, Poggio, Teresa, Gorantla, Sivahari Prasad, Rückert, Tamina, Schmitt-Graeff, Annette, Gengenbacher, Anina, Paschka, Peter, Baldus, Claudia, Zeiser, Robert, Vassiliou, George S., Bradley, Allan, Duyster, Justus, Illert, Anna Lena
Veröffentlicht in Blood (2019)

Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1)

von Meyer, Tatjana, Jahn, Nikolaus, Lindner, Stefanie, Röhner, Linda, Dolnik, Anna, Weber, Daniela, Scheffold, Annika, Köpff, Simon, Paschka, Peter, Gaidzik, Verena I., Heckl, Dirk, Wiese, Sebastian, Ebert, Benjamin L., Döhner, Hartmut, Bullinger, Lars, Döhner, Konstanze, Krönke, Jan
Veröffentlicht in Leukemia (2019)

Long-term disease-free survivors with cytogenetically normal acute myeloid leukemia and MLL partial tandem duplication: a Cancer and Leukemia Group B study

von Whitman, Susan P., Ruppert, Amy S., Marcucci, Guido, Mrózek, Krzysztof, Paschka, Peter, Langer, Christian, Baldus, Claudia D., Wen, Jing, Vukosavljevic, Tamara, Powell, Bayard L., Carroll, Andrew J., Kolitz, Jonathan E., Larson, Richard A., Caligiuri, Michael A., Bloomfield, Clara D.
Veröffentlicht 2007

FLT3 D835/I836 mutations are associated with poor disease-free survival and a distinct gene-expression signature among younger adults with de novo cytogenetically normal acute myel...

von Whitman, Susan P., Ruppert, Amy S., Radmacher, Michael D., Mrózek, Krzysztof, Paschka, Peter, Langer, Christian, Baldus, Claudia D., Wen, Jing, Racke, Frederick, Powell, Bayard L., Kolitz, Jonathan E., Larson, Richard A., Caligiuri, Michael A., Marcucci, Guido, Bloomfield, Clara D.
Veröffentlicht 2008

Protein phosphatase 4 regulatory subunit 2 (PPP4R2) is recurrently deleted in acute myeloid leukemia and required for efficient DNA double strand break repair

von Herzig, Julia K., Bullinger, Lars, Tasdogan, Alpaslan, Zimmermann, Philipp, Schlegel, Martin, Teleanu, Veronica, Weber, Daniela, Rücker, Frank G., Paschka, Peter, Dolnik, Anna, Schneider, Edith, Kuchenbauer, Florian, Heidel, Florian H., Buske, Christian, Döhner, Hartmut, Döhner, Konstanze, Gaidzik, Verena I.
Veröffentlicht in Oncotarget (2017)

Wilms’ Tumor 1 Gene Mutations Independently Predict Poor Outcome in Adults With Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

von Paschka, Peter, Marcucci, Guido, Ruppert, Amy S., Whitman, Susan P., Mrózek, Krzysztof, Maharry, Kati, Langer, Christian, Baldus, Claudia D., Zhao, Weiqiang, Powell, Bayard L., Baer, Maria R., Carroll, Andrew J., Caligiuri, Michael A., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.
Veröffentlicht 2008

High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60...

von Langer, Christian, Radmacher, Michael D., Ruppert, Amy S., Whitman, Susan P., Paschka, Peter, Mrózek, Krzysztof, Baldus, Claudia D., Vukosavljevic, Tamara, Liu, Chang-Gong, Ross, Mary E., Powell, Bayard L., de la Chapelle, Albert, Kolitz, Jonathan E., Larson, Richard A., Marcucci, Guido, Bloomfield, Clara D.
Veröffentlicht 2008

Prognostic Importance of MN1 Transcript Levels, and Biologic Insights From MN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia:...

von Langer, Christian, Marcucci, Guido, Holland, Kelsi B., Radmacher, Michael D., Maharry, Kati, Paschka, Peter, Whitman, Susan P., Mrózek, Krzysztof, Baldus, Claudia D., Vij, Ravi, Powell, Bayard L., Carroll, Andrew J., Kolitz, Jonathan E., Caligiuri, Michael A., Larson, Richard A., Bloomfield, Clara D.
Veröffentlicht 2009

Phase I clinical study of RG7356, an anti-CD44 humanized antibody, in patients with acute myeloid leukemia

von Vey, Norbert, Delaunay, Jacques, Martinelli, Giovanni, Fiedler, Walter, Raffoux, Emmanuel, Prebet, Thomas, Gomez-Roca, Carlos, Papayannidis, Cristina, Kebenko, Maxim, Paschka, Peter, Christen, Randolph, Guarin, Ernesto, Bröske, Ann-Marie, Baehner, Monika, Brewster, Michael, Walz, Antje-Christine, Michielin, Francesca, Runza, Valeria, Meresse, Valerie, Recher, Christian
Veröffentlicht in Oncotarget (2016)

Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular F...

von Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Vukosavljevic, Tamara, Paschka, Peter, Whitman, Susan P., Langer, Christian, Baldus, Claudia D., Liu, Chang-Gong, Ruppert, Amy S., Powell, Bayard L., Carroll, Andrew J., Caligiuri, Michael A., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.
Veröffentlicht 2008

An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

von Metzeler, Klaus H., Hummel, Manuela, Bloomfield, Clara D., Spiekermann, Karsten, Braess, Jan, Sauerland, Maria-Cristina, Heinecke, Achim, Radmacher, Michael, Marcucci, Guido, Whitman, Susan P., Maharry, Kati, Paschka, Peter, Larson, Richard A., Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Buske, Christian
Veröffentlicht 2008