Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study

PURPOSE: To evaluate the prognostic significance of CEBPA mutations in the context of established molecular markers in cytogenetically normal (CN) acute myeloid leukemia (AML) and gain biologic insights into leukemogenesis of the CN-AML molecular high-risk subset (FLT3 internal tandem duplication [I...

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Главные авторы: Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Vukosavljevic, Tamara, Paschka, Peter, Whitman, Susan P., Langer, Christian, Baldus, Claudia D., Liu, Chang-Gong, Ruppert, Amy S., Powell, Bayard L., Carroll, Andrew J., Caligiuri, Michael A., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2008
Предметы:
Leukemia and Bone Marrow Transplantation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652095/
https://ncbi.nlm.nih.gov/pubmed/18809607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.5554
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