Prognostic Significance of, and Gene and MicroRNA Expression Signatures Associated With, CEBPA Mutations in Cytogenetically Normal Acute Myeloid Leukemia With High-Risk Molecular Features: A Cancer and Leukemia Group B Study

PURPOSE: To evaluate the prognostic significance of CEBPA mutations in the context of established molecular markers in cytogenetically normal (CN) acute myeloid leukemia (AML) and gain biologic insights into leukemogenesis of the CN-AML molecular high-risk subset (FLT3 internal tandem duplication [I...

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Main Authors: Marcucci, Guido, Maharry, Kati, Radmacher, Michael D., Mrózek, Krzysztof, Vukosavljevic, Tamara, Paschka, Peter, Whitman, Susan P., Langer, Christian, Baldus, Claudia D., Liu, Chang-Gong, Ruppert, Amy S., Powell, Bayard L., Carroll, Andrew J., Caligiuri, Michael A., Kolitz, Jonathan E., Larson, Richard A., Bloomfield, Clara D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Clinical Oncology 2008
Teme:
Leukemia and Bone Marrow Transplantation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652095/
https://ncbi.nlm.nih.gov/pubmed/18809607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.5554
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