An 86-probe-set gene-expression signature predicts survival in cytogenetically normal acute myeloid leukemia

Patients with cytogenetically normal acute myeloid leukemia (CN-AML) show heterogeneous treatment outcomes. We used gene-expression profiling to develop a gene signature that predicts overall survival (OS) in CN-AML. Based on data from 163 patients treated in the German AMLCG 1999 trial and analyzed...

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Detalhes bibliográficos
Main Authors: Metzeler, Klaus H., Hummel, Manuela, Bloomfield, Clara D., Spiekermann, Karsten, Braess, Jan, Sauerland, Maria-Cristina, Heinecke, Achim, Radmacher, Michael, Marcucci, Guido, Whitman, Susan P., Maharry, Kati, Paschka, Peter, Larson, Richard A., Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Mansmann, Ulrich, Hiddemann, Wolfgang, Bohlander, Stefan K., Buske, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2008
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954679/
https://ncbi.nlm.nih.gov/pubmed/18716133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-134411
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