RUNX1 mutations in cytogenetically normal acute myeloid leukemia are associated with a poor prognosis and up-regulation of lymphoid genes

BACKGROUND: The RUNX1 (AML1) gene is a frequent mutational target in myelodysplastic syndromes and acute myeloid leukemia. Previous studies suggested that RUNX1 mutations may have pathological and prognostic implications. DESIGN AND METHODS: We screened 93 patients with cytogenetically normal acute...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Greif, Philipp A., Konstandin, Nikola P., Metzeler, Klaus H., Herold, Tobias, Pasalic, Zlatana, Ksienzyk, Bianka, Dufour, Annika, Schneider, Friederike, Schneider, Stephanie, Kakadia, Purvi M., Braess, Jan, Sauerland, Maria Cristina, Berdel, Wolfgang E., Büchner, Thomas, Woermann, Bernhard J., Hiddemann, Wolfgang, Spiekermann, Karsten, Bohlander, Stefan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3590097/
https://ncbi.nlm.nih.gov/pubmed/22689681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.064667
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados