Impressive thrombocytosis evolving in a patient with a BCR-ABL positive CML in major molecular response during dasatinib treatment unmasks an additional JAK2V617F

Por Pastore, Friederike, Schneider, Stephanie, Christ, Oliver, Hiddemann, Wolfgang, Spiekermann, Karsten
Publicado em 2013

The Role of Therapeutic Leukapheresis in Hyperleukocytotic AML

Por Pastore, Friederike, Pastore, Alessandro, Wittmann, Georg, Hiddemann, Wolfgang, Spiekermann, Karsten
Publicado em 2014

Frequency of hematologic and solid malignancies in the family history of 50 patients with acute myeloid leukemia – a single center analysis

Por Sandner, Anne-Sophie, Weggel, Ramona, Mehraein, Yasmin, Schneider, Stephanie, Hiddemann, Wolfgang, Spiekermann, Karsten
Publicado no PLoS One (2019)

Microenvironmental Hypoxia regulates FLT3 expression and biology in AML

Por Sironi, Silvia, Wagner, Michaela, Kuett, Alexander, Drolle, Heidrun, Polzer, Harald, Spiekermann, Karsten, Rieger, Christina, Fiegl, Michael
Publicado no Sci Rep (2015)

Combination of Complement-Dependent Cytotoxicity and Relative Fluorescent Quantification of HLA Length Polymorphisms Facilitates the Detection of a Loss of Heterozygosity

Por Witter, Klaus, Reibke, Roland, Subklewe, Marion, Zahn, Robert, Kauke, Teresa, Spiekermann, Karsten, Spannagl, Michael, Tischer, Johanna, Hiddemann, Wolfgang, Dick, Andrea
Publicado em 2014

Response assessment in acute myeloid leukemia by flow cytometry supersedes cytomorphology at time of aplasia, amends cases without molecular residual disease marker and serves as a...

Por Köhnke, Thomas, Bücklein, Veit, Rechkemmer, Sandra, Schneider, Stephanie, Rothenberg-Thurley, Maja, Metzeler, Klaus H., Sauerland, Maria-Cristina, Hiddemann, Wolfgang, Spiekermann, Karsten, Subklewe, Marion
Publicado no Haematologica (2019)

An ETV6-ABL1 fusion in a patient with chronic myeloproliferative neoplasm: Initial response to Imatinib followed by rapid transformation into ALL

Por Kakadia, Purvi M., Schmidmaier, Ralf, Völkl, Andreas, Schneider, Irene, Huk, Natalia, Schneider, Stephanie, Panzner, Gerda, Neidel, Ulrike, Fritz, Barbara, Spiekermann, Karsten, Bohlander, Stefan K.
Publicado no Leuk Res Rep (2016)

Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis

Por Grunwald, Victoria V., Hentrich, Marcus, Schiel, Xaver, Dufour, Annika, Schneider, Stephanie, Neusser, Michaela, Subklewe, Marion, Fiegl, Michael, Hiddemann, Wolfgang, Spiekermann, Karsten, Rothenberg-Thurley, Maja, Metzeler, Klaus H.
Publicado no Blood Adv (2019)

Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

Por Alachkar, Houda, Mutonga, Martin B.G., Metzeler, Klaus H., Fulton, Noreen, Malnassy, Gregory, Herold, Tobias, Spiekermann, Karsten, Bohlander, Stefan K., Hiddemann, Wolfgang, Matsuo, Yo, Stock, Wendy, Nakamura, Yusuke
Publicado no Oncotarget (2014)

Young woman with mild bone marrow dysplasia, GATA2 and ASXL1 mutation treated with allogeneic hematopoietic stem cell transplantation

Por Lübking, Anna, Vosberg, Sebastian, Konstandin, Nikola P., Dufour, Annika, Graf, Alexander, Krebs, Stefan, Blum, Helmut, Weber, Axel, Lenhoff, Stig, Ehinger, Mats, Spiekermann, Karsten, Greif, Philipp A., Cammenga, Jörg
Publicado no Leuk Res Rep (2015)

Long-term follow-up of cytogenetically normal CEBPA-mutated AML

Por Pastore, Friederike, Kling, Daniela, Hoster, Eva, Dufour, Annika, Konstandin, Nikola P, Schneider, Stephanie, Sauerland, Maria C, Berdel, Wolfgang E, Buechner, Thomas, Woermann, Bernhard, Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten
Publicado em 2014

The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor

Por Sandhöfer, Nadine, Bauer, Julia, Reiter, Katrin, Dufour, Annika, Rothenberg, Maja, Konstandin, Nikola P., Zellmeier, Evelyn, Tizazu, Belay, Greif, Philipp A., Metzeler, Klaus H., Hiddemann, Wolfgang, Polzer, Harald, Spiekermann, Karsten
Publicado no Sci Rep (2016)

Immunotherapy using bispecific T cell engager (BiTE(®)) antibodies: preclinical and clinical experience in acute leukemia

Por Subklewe, Marion, Topp, Max, Krupka, Christina, Kufer, Peter, Kischel, Roman, Köhnke, Thomas, Baeuerle, Patrick, Zugmaier, Gerhard, Frankel, Stanley, Maniar, Tapan, Newhall, Katie, Spiekermann, Karsten, Riethmueller, Gert, Nagorsen, Dirk, Hiddemann, Wolfgang
Publicado no J Immunother Cancer (2014)

Activating FLT3 Mutants Show Distinct Gain-of-Function Phenotypes In Vitro and a Characteristic Signaling Pathway Profile Associated with Prognosis in Acute Myeloid Leukemia

Por Janke, Hanna, Pastore, Friederike, Schumacher, Daniela, Herold, Tobias, Hopfner, Karl-Peter, Schneider, Stephanie, Berdel, Wolfgang E., Büchner, Thomas, Woermann, Bernhard J., Subklewe, Marion, Bohlander, Stefan K., Hiddemann, Wolfgang, Spiekermann, Karsten, Polzer, Harald
Publicado em 2014

Relapse of acute myeloid leukemia after allogeneic stem cell transplantation is associated with gain of WT1 alterations and high mutation load

Por Vosberg, Sebastian, Hartmann, Luise, Metzeler, Klaus H., Konstandin, Nikola P., Schneider, Stephanie, Varadharajan, Ashok, Hauser, Andreas, Krebs, Stefan, Blum, Helmut, Bohlander, Stefan K., Hiddemann, Wolfgang, Tischer, Johanna, Spiekermann, Karsten, Greif, Philipp A.
Publicado no Haematologica (2018)

The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML

Por Pastore, Friederike, Greif, Philipp A., Schneider, Stephanie, Ksienzyk, Bianka, Mellert, Gudrun, Zellmeier, Evelyn, Braess, Jan, Sauerland, Cristina M., Heinecke, Achim, Krug, Utz, Berdel, Wolfgang E., Buechner, Thomas, Woermann, Bernhard, Hiddemann, Wolfgang, Spiekermann, Karsten
Publicado em 2014

Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse

Por Hubmann, Max, Köhnke, Thomas, Hoster, Eva, Schneider, Stephanie, Dufour, Annika, Zellmeier, Evelyn, Fiegl, Michael, Braess, Jan, Bohlander, Stefan K., Subklewe, Marion, Sauerland, Maria-Cristina, Berdel, Wolfgang E., Büchner, Thomas, Wörmann, Bernhard, Hiddemann, Wolfgang, Spiekermann, Karsten
Publicado em 2014

An Advanced Preclinical Mouse Model for Acute Myeloid Leukemia Using Patients' Cells of Various Genetic Subgroups and In Vivo Bioluminescence Imaging

Por Vick, Binje, Rothenberg, Maja, Sandhöfer, Nadine, Carlet, Michela, Finkenzeller, Cornelia, Krupka, Christina, Grunert, Michaela, Trumpp, Andreas, Corbacioglu, Selim, Ebinger, Martin, André, Maya C., Hiddemann, Wolfgang, Schneider, Stephanie, Subklewe, Marion, Metzeler, Klaus H., Spiekermann, Karsten, Jeremias, Irmela
Publicado no PLoS One (2015)

The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice

Por Schessl, Christina, Rawat, Vijay P.S., Cusan, Monica, Deshpande, Aniruddha, Kohl, Tobias M., Rosten, Patricia M., Spiekermann, Karsten, Humphries, R. Keith, Schnittger, Susanne, Kern, Wolfgang, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian
Publicado em 2005

Subtype assignment of CLL based on B-cell subset associated gene signatures from normal bone marrow – A proof of concept study

Por Nørgaard, Caroline Holm, Jakobsen, Lasse Hjort, Gentles, Andrew J., Dybkær, Karen, El-Galaly, Tarec Christoffer, Bødker, Julie Støve, Schmitz, Alexander, Johansen, Preben, Herold, Tobias, Spiekermann, Karsten, Brown, Jennifer R., Klitgaard, Josephine L., Johnsen, Hans Erik, Bøgsted, Martin
Publicado no PLoS One (2018)