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The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice
The molecular characterization of leukemia has demonstrated that genetic alterations in the leukemic clone frequently fall into 2 classes, those affecting transcription factors (e.g., AML1-ETO) and mutations affecting genes involved in signal transduction (e.g., activating mutations of FLT3 and KIT)...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1174917/ https://ncbi.nlm.nih.gov/pubmed/16025155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24225 |
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