The AML1-ETO fusion gene and the FLT3 length mutation collaborate in inducing acute leukemia in mice

The molecular characterization of leukemia has demonstrated that genetic alterations in the leukemic clone frequently fall into 2 classes, those affecting transcription factors (e.g., AML1-ETO) and mutations affecting genes involved in signal transduction (e.g., activating mutations of FLT3 and KIT)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Schessl, Christina, Rawat, Vijay P.S., Cusan, Monica, Deshpande, Aniruddha, Kohl, Tobias M., Rosten, Patricia M., Spiekermann, Karsten, Humphries, R. Keith, Schnittger, Susanne, Kern, Wolfgang, Hiddemann, Wolfgang, Quintanilla-Martinez, Leticia, Bohlander, Stefan K., Feuring-Buske, Michaela, Buske, Christian
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical Investigation 2005
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1174917/
https://ncbi.nlm.nih.gov/pubmed/16025155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24225
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