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Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia

Maternal embryonic leucine-zipper kinase (MELK), which was reported to be frequently up-regulated in various types of solid cancer, plays critical roles in formation and maintenance of cancer stem cells. However, little is known about the relevance of this kinase in hematologic malignancies. Here we...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Alachkar, Houda, Mutonga, Martin B.G., Metzeler, Klaus H., Fulton, Noreen, Malnassy, Gregory, Herold, Tobias, Spiekermann, Karsten, Bohlander, Stefan K., Hiddemann, Wolfgang, Matsuo, Yo, Stock, Wendy, Nakamura, Yusuke
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323011/
https://ncbi.nlm.nih.gov/pubmed/25365263
תגים: הוספת תג
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