Patients with spontaneous remission of high-risk MDS and AML show persistent preleukemic clonal hematopoiesis

We report longitudinal mutational analyses of 2 patients with high-risk MDS and AML experiencing spontaneous disease remissions. Both patients had persistent clonal hematopoiesis during remission, harboring all but 1 of the mutations from the initial diagnostic sample.

Guardat en:
Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Grunwald, Victoria V., Hentrich, Marcus, Schiel, Xaver, Dufour, Annika, Schneider, Stephanie, Neusser, Michaela, Subklewe, Marion, Fiegl, Michael, Hiddemann, Wolfgang, Spiekermann, Karsten, Rothenberg-Thurley, Maja, Metzeler, Klaus H.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2019
Matèries:
Exceptional Case Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6759731/
https://ncbi.nlm.nih.gov/pubmed/31515231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019000265
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