Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA

Biallelic mutations of the CCAAT/enhancer binding protein α (CEBPA) gene define a distinct genetic entity of acute myeloid leukemia (AML) with favorable prognosis. The presence of GATA2 and CSF3R mutations that are specifically associated with this subgroup but not mutated in all samples suggests a...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: Konstandin, Nikola P., Pastore, Friederike, Herold, Tobias, Dufour, Annika, Rothenberg-Thurley, Maja, Hinrichsen, Tanja, Ksienzyk, Bianka, Tschuri, Sebastian, Schneider, Stephanie, Hoster, Eva, Berdel, Wolfgang E., Woermann, Bernhard J., Sauerland, Maria C., Braess, Jan, Bohlander, Stefan K., Klein, Hanns-Georg, Hiddemann, Wolfgang, Metzeler, Klaus H., Spiekermann, Karsten
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2018
Pynciau:
Myeloid Neoplasia
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199648/
https://ncbi.nlm.nih.gov/pubmed/30337300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018016840
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