Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA

Biallelic mutations of the CCAAT/enhancer binding protein α (CEBPA) gene define a distinct genetic entity of acute myeloid leukemia (AML) with favorable prognosis. The presence of GATA2 and CSF3R mutations that are specifically associated with this subgroup but not mutated in all samples suggests a...

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Pubblicato in:Blood Adv
Autori principali: Konstandin, Nikola P., Pastore, Friederike, Herold, Tobias, Dufour, Annika, Rothenberg-Thurley, Maja, Hinrichsen, Tanja, Ksienzyk, Bianka, Tschuri, Sebastian, Schneider, Stephanie, Hoster, Eva, Berdel, Wolfgang E., Woermann, Bernhard J., Sauerland, Maria C., Braess, Jan, Bohlander, Stefan K., Klein, Hanns-Georg, Hiddemann, Wolfgang, Metzeler, Klaus H., Spiekermann, Karsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2018
Soggetti:
Myeloid Neoplasia
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199648/
https://ncbi.nlm.nih.gov/pubmed/30337300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018016840
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