Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older

A cute myeloid leukemia is a disease of the elderly (median age at diagnosis, 65–70 years). The prognosis of older acute myeloid leukemia patients is generally poor. While genetic markers have become important tools for risk stratification and treatment selection in young and middle-aged patients, t...

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Pubblicato in:Haematologica
Autori principali: Prassek, Victoria V., Rothenberg-Thurley, Maja, Sauerland, Maria C., Herold, Tobias, Janke, Hanna, Ksienzyk, Bianka, Konstandin, Nikola P., Goerlich, Dennis, Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E., Wörmann, Bernhard, Braess, Jan, Schneider, Stephanie, Subklewe, Marion, Bohlander, Stefan K., Hiddemann, Wolfgang, Spiekermann, Karsten, Metzeler, Klaus H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ferrata Storti Foundation 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278991/
https://ncbi.nlm.nih.gov/pubmed/29903761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.191536
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