NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia

Activating mutations in FMS-like tyrosine kinase receptor-3 (FLT3) and Nucleophosmin-1 (NPM1) are most frequent alterations in acute myeloid leukemia (AML), and are often coincidental. The mutational status of NPM1 has strong prognostic relevance to patients with point mutations of the FLT3 tyrosine...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Rudorf, Alina, Müller, Tony Andreas, Klingeberg, Cathrin, Kreutmair, Stefanie, Poggio, Teresa, Gorantla, Sivahari Prasad, Rückert, Tamina, Schmitt-Graeff, Annette, Gengenbacher, Anina, Paschka, Peter, Baldus, Claudia, Zeiser, Robert, Vassiliou, George S., Bradley, Allan, Duyster, Justus, Illert, Anna Lena
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2019
Fag:
Myeloid Neoplasia
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6659255/
https://ncbi.nlm.nih.gov/pubmed/31186273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2018883140
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker