Proteomic Phosphosite Analysis Identified Crucial NPM-ALK-Mediated NIPA Serine and Threonine Residues

Anaplastic large-cell lymphoma (ALCL) is an aggressive non-Hodgkin lymphoma that shows in 60% of cases a translocation t(2;5)(p23;q35), which leads to the expression of the oncogenic kinase NPM-ALK. The nuclear interaction partner of ALK (NIPA) defines an E3-SCF ligase that contributes to the timing...

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Pubblicato in:Int J Mol Sci
Autori principali: Gengenbacher, Anina, Müller-Rudorf, Alina, Poggio, Teresa, Gräßel, Linda, Dumit, Veronica I., Kreutmair, Stefanie, Lippert, Lena J., Duyster, Justus, Illert, Anna L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721280/
https://ncbi.nlm.nih.gov/pubmed/31434245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20164060
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